The interplay of reactive oxygen species, hypoxia, inflammation, and sirtuins in cancer initiation and progression

M Tafani, L Sansone, F Limana… - Oxidative medicine …, 2016 - Wiley Online Library
The presence of ROS is a constant feature in living cells metabolizing O2. ROS
concentration and compartmentation determine their physiological or pathological effects …

Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight

T Hussain, M Kandeel, E Metwally, G Murtaza… - Frontiers in …, 2023 - frontiersin.org
Male infertility is a widely debated issue that affects males globally. There are several
mechanisms involved. Oxidative stress is accepted to be the main contributing factor, with …

Exosome composition and seminal plasma proteome: A promising source of biomarkers of male infertility

L Candenas, R Chianese - International journal of molecular sciences, 2020 - mdpi.com
Infertility has become a global health issue, with approximately 50% of infertility cases
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …

The enigmatic seminal plasma: a proteomics insight from ejaculation to fertilization

L Samanta, R Parida, TR Dias, A Agarwal - Reproductive Biology and …, 2018 - Springer
Background The 'omics' approach for a noninvasive diagnosis of male reproductive system
disorders has gained momentum during the last decade, particularly from a screening and …

[PDF][PDF] Sperm mitochondrial dysfunction and oxidative stress as possible reasons for isolated asthenozoospermia

K Nowicka-Bauer, A Lepczynski, M Ozgo… - … of Physiology and …, 2018 - bibliotekanauki.pl
Reduced sperm motility, defined as asthenozoospermia, is a frequent cause of male
infertility, and is mainly connected with the dysfunction of sperm mitochondria. The aim of …

[HTML][HTML] MiOXSYS: a novel method of measuring oxidation reduction potential in semen and seminal plasma

A Agarwal, R Sharma, S Roychoudhury, S Du Plessis… - Fertility and sterility, 2016 - Elsevier
Objective To measure oxidative reduction potential (ORP) in semen and seminal plasma
and to establish their reference levels. Design ORP levels were measured in semen and …

Abstinence time and its impact on basic and advanced semen parameters

A Agarwal, S Gupta, S Du Plessis, R Sharma… - Urology, 2016 - Elsevier
Objective To assess the effect of ejaculatory abstinence (EA) periods on routine and
advanced sperm tests. Methods Men with normozoospermia provided semen samples after …

Proteomics, oxidative stress and male infertility

A Agarwal, D Durairajanayagam, J Halabi… - Reproductive …, 2014 - Elsevier
Oxidative stress has been established as one of the main causes of male infertility and has
been implicated in many diseases associated with infertile men. It results from high …

Omics and male infertility: highlighting the application of transcriptomic data

TS Omolaoye, VA Omolaoye, RK Kandasamy… - Life, 2022 - mdpi.com
Male infertility is a multifaceted disorder affecting approximately 50% of male partners in
infertile couples. Over the years, male infertility has been diagnosed mainly through semen …

Seminal plasma proteomic biomarkers of oxidative stress

R Cannarella, A Crafa, F Barbagallo… - International Journal of …, 2020 - mdpi.com
The prevalence of idiopathic male infertility is high, up to 75% of patients with abnormal
sperm parameters. Hence, the research of its causes is mandatory. Oxidative stress (OS) …