The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

Galleria mellonella larvae have been widely used as alternative non-mammalian models for
the study of fungal virulence and pathogenesis. The larvae can be acquired in small …

Iron is an essential nutrient for all organisms. For pathogenic fungi, iron is essential for the
success of infection. Thus, these organisms have developed high affinity iron uptake …

The yeast SKI (superkiller) complex was originally identified from cells that were infected by
the M 'killer'virus. Ski2, as the core of the SKI complex, is a cytoplasmic cofactor and …

Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work,
we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates …

Similar to other yeasts, the human pathogen Candida glabrata ages when it undergoes
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …

Cryptococcus neoformans causes meningoencephalitis in immunocompromised individuals,
which is treated with fluconazole (FLC) monotherapy when resources are limited. This can …

As Cryptococcus neoformans mother cells generationally age, their cell walls become
thicker and cell-wall associated virulence factors are upregulated. Antiphagocytic protein 1 …

The fungal pathogen, Cryptococcus neoformans, has been shown to undergo replicative
aging. Old cells are characterized by advanced generational age and phenotypic changes …

Cryptococcus neoformans is an opportunistic fungal pathogen known for its remarkable
ability to infect and subvert phagocytes. This ability provides survival and persistence within …