Adult neurogenesis and mental illness

TJ Schoenfeld, HA Cameron - Neuropsychopharmacology, 2015 - nature.com
Several lines of evidence suggest that adult neurogenesis, the production of new neurons in
adulthood, may play a role in psychiatric disorders, including depression, anxiety, and …

Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: Prospective 12-month follow-up

N Gukasyan, AK Davis, FS Barrett… - Journal of …, 2022 - journals.sagepub.com
Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

Implementing measurement-based care for depression: practical solutions for psychiatrists and primary care physicians

RH Hong, JK Murphy, EE Michalak… - Neuropsychiatric …, 2021 - Taylor & Francis
Measurement-based care (MBC) can be defined as the clinical practice in which care
providers collect patient data through validated outcome scales and use the results to guide …

Clinical implementation of pharmacogenetic decision support tools for antidepressant drug prescribing

Z Zeier, LL Carpenter, NH Kalin… - American Journal of …, 2018 - Am Psychiatric Assoc
The accrual and analysis of genomic sequencing data have identified specific genetic
variants that are associated with major depressive disorder. Moreover, substantial …

Elucidation of the behavioral program and neuronal network encoded by dorsal raphe serotonergic neurons

DJ Urban, H Zhu, CA Marcinkiewcz… - …, 2016 - nature.com
Elucidating how the brain's serotonergic network mediates diverse behavioral actions over
both relatively short (minutes–hours) and long period of time (days–weeks) remains a major …

Mechanisms of antidepressant resistance

W El-Hage, S Leman, V Camus… - Frontiers in …, 2013 - frontiersin.org
Depression is one of the most frequent and severe mental disorder. Since the discovery of
antidepressant (AD) properties of the imipramine and then after of other tricyclic compounds …

When should governments increase the supply of psychiatric beds?

S Allison, T Bastiampillai, J Licinio, DA Fuller… - Molecular …, 2018 - nature.com
Low numbers of hospital-based psychiatric beds create problems for people with severe
mental illness (SMI), when they face extended emergency department (ED) waits, higher …

Early switching strategies in antidepressant non-responders: current evidence and future research directions

PA Kudlow, RS McIntyre, RW Lam - CNS drugs, 2014 - Springer
Studies have found that up to two-thirds of patients with major depressive disorder (MDD) do
not fully respond to the first antidepressant. While switching antidepressants is a common …

[HTML][HTML] Early symptom improvement at 10 sessions as a predictor of rTMS treatment outcome in major depression

K Feffer, HH Lee, F Mansouri, P Giacobbe… - Brain stimulation, 2018 - Elsevier
Background Predicting rTMS nonresponse could be helpful in sparing patients from futile
treatment, and in improving use of limited rTMS resources. While several predictive …

Lipids in major depressive disorder: new kids on the block or old friends revisited?

AR van der Heijden, T Houben - Frontiers in Psychiatry, 2023 - frontiersin.org
Major depressive disorder (MDD) is a psychiatric mood disorder that results in substantial
functional impairment and is characterized by symptoms such as depressed mood …