Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system
AB Nesburn, I Bettahi, X Zhang, X Zhu, W Chamberlain… - The ocular …, 2006 - Elsevier
Mucosal vaccination is proving to be one of the greatest challenges in modern vaccine
development. Although ocular mucosal immunity is highly beneficial for achieving protective …
development. Although ocular mucosal immunity is highly beneficial for achieving protective …
CpG oligodeoxynucleotides as DNA adjuvants in vertebrates and their applications in immunotherapy
HC Chaung - International immunopharmacology, 2006 - Elsevier
The genomes of bacterial and viral DNA contain a much higher frequency of unmethylated
CpG dinucleotides than those of vertebrates. This difference in genome structure allows the …
CpG dinucleotides than those of vertebrates. This difference in genome structure allows the …
Molecular cloning and expression studies of the adapter molecule myeloid differentiation factor 88 (MyD88) in turbot (Scophthalmus maximus)
JY Lin, GB Hu, CH Yu, S Li, QM Liu… - Developmental & …, 2015 - Elsevier
Abstract Myeloid differentiation factor 88 (MyD88) is an adapter protein involved in the
interleukin-1 receptor (IL-1R) and Toll-like receptor (TLR)-mediated activation of nuclear …
interleukin-1 receptor (IL-1R) and Toll-like receptor (TLR)-mediated activation of nuclear …
A species-specific activation of Toll-like receptor signaling in bovine and sheep bronchial epithelial cells triggered by Mycobacterial infections
Y Ma, F Han, J Liang, J Yang, J Shi, J Xue, L Yang… - Molecular …, 2016 - Elsevier
Pulmonary tuberculosis caused by a Mycobacterium infection remains a major public health
problem in most part of the world, in part owing to the transmission of its pathogens between …
problem in most part of the world, in part owing to the transmission of its pathogens between …
DNA vaccines and their application against parasites-promise, limitations and potential solutions Peter M. Smooker', Adam Rainczuk², Nicholas Kennedy², and Terry …
PM Smooker, A Rainczuk, N Kennedy… - Biotechnology annual …, 2004 - books.google.com
DNA or nucleic acid vaccines are being evaluated for efficacy against a range of parasitic
diseases. Data from studies in rodent model systems have provided proof of principle that …
diseases. Data from studies in rodent model systems have provided proof of principle that …
Cytokine induction by immunostimulatory DNA in porcine PBMC is impaired by a hairpin forming sequence motif from the genome of Porcine Circovirus type 2 (PCV2)
FH Wikström, C Fossum, L Fuxler, R Kruse… - Veterinary immunology …, 2011 - Elsevier
Porcine Circovirus type 2 (PCV2) can cause postweaning multisystemic wasting syndrome
(PMWS) in young pigs with severe immunosuppression as a major characteristic of the …
(PMWS) in young pigs with severe immunosuppression as a major characteristic of the …
Macrophages and dendritic cells
Macrophages, monocytes, and conventional dendritic cells (cDCs), together with B
lymphocytes, are termed antigen-presenting cells (APCs). Monocytes and cDCs differentiate …
lymphocytes, are termed antigen-presenting cells (APCs). Monocytes and cDCs differentiate …
Porcine interleukin-3 enhances DNA vaccination against classical swine fever
M Andrew, K Morris, B Coupar, K Sproat, P Oke… - Vaccine, 2006 - Elsevier
DNA vectors can be used to deliver vaccine antigens that stimulate effective protective
immunity in mice, but in larger, outbred animal species, the protective efficacy is lower or …
immunity in mice, but in larger, outbred animal species, the protective efficacy is lower or …
Characterization of three distinct CpG oligonucleotide classes which differ in ability to induce IFN α/β activity and cell proliferation in Atlantic salmon (Salmo salar L.) …
G Strandskog, T Ellingsen, JB Jørgensen - Developmental & Comparative …, 2007 - Elsevier
Oligodeoxynucleotides (ODNs) containing unmethylated CpG dinucleotides within specific
sequence contexts (CpG motifs) are in humans divided into three distinct classes (A, B and …
sequence contexts (CpG motifs) are in humans divided into three distinct classes (A, B and …
Formulation with CpG ODN enhances antibody responses to an equine influenza virus vaccine
AM Lopez, R Hecker, G Mutwiri, LA Babiuk… - Veterinary immunology …, 2006 - Elsevier
Previous studies have shown that protection against equine influenza virus (EIV) is partially
mediated by virus-specific IgGa and IgGb. In this study we tested whether addition of a CpG …
mediated by virus-specific IgGa and IgGb. In this study we tested whether addition of a CpG …