In vivo effects of oligodeoxynucleotides containing synthetic immunostimulatory motifs in the immune response to swine streptococcic septicemia vaccine in weaned …

Z Linghua, T Xingshan, Z Fengzhen - Molecular Immunology, 2007 - Elsevier
The diverse immunostimulatory effects of CpG oligodeoxynucleotides (CpG ODN) have
been demonstrated extensively in mice and human. Although the immunoadjuvant effects of …

Carbon nanotubes significantly enhance the biological activity of CpG ODN in chickens

J Tomporowski, JM Heer, B Allan, S Gomis… - International Journal of …, 2019 - Elsevier
Synthetic unmethylated cytidine-phosphate-guanosine oligodeoxynucleotides (CpG ODN) is
an effective immune stimulant in chicken. To be effective CpG dosage requirement is high …

Immunotherapeutic potential of CpG oligodeoxynucleotides in veterinary species

A Manuja, BK Manuja, J Kaushik… - …, 2013 - Taylor & Francis
Innate immunity plays a critical role in host defense against infectious diseases by
discriminating between self and infectious non-self. The recognition of infectious non-self …

CpG 寡脱氧核苷酸的免疫刺激特性及应用研究进展

司兴奎, 陈建红, 张济培, 顾万军 - 动物医学进展, 2008 - cqvip.com
CpG 基序是指含有非甲基化的胞嘧啶(C) 和鸟嘌呤(G) 二核苷酸为核心序列的基序为5′-RD-
CpG-YY-3′ 的DNA 或寡脱氧核苷酸序列, 是DNA 具有免疫刺激活性的结构基础. 随着对CpG …

Recombinant plasmids containing CpG with porcine host defense peptides (PR-39/pBD-1) modulates the innate and adaptive intestinal immune responses (including …

S Zhang, H Cai, D Cao, J Deng, J Jia, J Li… - International …, 2019 - Elsevier
CpG oligodeoxynucleotides (CpG-ODN) is an immunoenhancer, which is composed of
unmethylated cytosine and guanine. Host Defense Peptides (HDPs) are small molecule …

Characterization of ovine Toll-like receptor 9 protein coding region, comparative analysis, detection of mutations and maedi visna infection

I Mikula Jr, I Mikula Sr - Developmental & Comparative Immunology, 2011 - Elsevier
One of the major roles of innate immunity system is the recognition and the determination of
the nature of the antigen. This ability is encompassed by specific receptors as Toll-like …

Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNα-producing cells and TLR9 mRNA …

A Dar, AK Nichani, P Benjamin, K Lai, H Soita… - Veterinary immunology …, 2008 - Elsevier
The immune stimulatory effects of synthetic CpG DNA, on porcine peripheral blood
mononuclear cells (PBMC) have been reported, but little is known about CpG-induced …

In vivo immunostimulatory effects of CpG ODN in newborn piglets

Z Linghua, T Xingshan, Z Fengzhen - Molecular immunology, 2007 - Elsevier
The in vivo immunoadjuvant effects of CpG oligodeoxynucleotides (CpG ODN) have been
studied extensively in mice and relatively fewer studies have been done in other species …

CpG-oligodeoxynucleotides inhibit RSV-enhanced allergic sensitisation in guinea pigs

F Tayyari, TC Sutton, HE Manson… - European Respiratory …, 2005 - Eur Respiratory Soc
Experimental respiratory syncytial virus (RSV) infection of guinea pigs is associated with
enhanced allergic sensitisation to inhaled ovalbumin (OA) and low-level viral persistence in …

Recombinant hvt vectors expressing antigens of avian pathogens and uses thereof

M Bublot, T Mebatsion, J Pritchard, P Linz - US Patent 9,114,108, 2015 - Google Patents
The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that
contain and express antigens of avian pathogens, compositions comprising the recombinant …