Principles of Vaccinology and Vaccine Immune Response

M Montoya, EZ Tchilian - Veterinary Vaccines: Principles and …, 2021 - Wiley Online Library
In this chapter, the authors review how the adaptive immune response protects against the
attack of pathogens, describing the major types of lymphocytes, B and T cells, and the …

Systemic innate immune responses following intrapulmonary delivery of CpG oligodeoxynucleotides in sheep

AK Nichani, MA Dar, AM Krieg, KK Mirakhur… - Veterinary immunology …, 2007 - Elsevier
Mucosal delivery of CpG oligodeoxynucleotide (ODN) in mice has been shown to induce
potent innate immunostimulatory responses and protection against infection. We evaluated …

CpG ODN 对传染性腔上囊病病毒活疫苗免疫效果的影响

崔烨, 田兴山, 张玲华, 李宗义 - 中国兽医科技, 2005 - cqvip.com
将120 只来航系SPF 鸡随机分成对照组, 注射CpG ODN 组, IBDV 活疫苗点眼免疫组及IBDV
活疫苗+ CpG ODN 免疫组, 每组30 只, 于7 日龄时对试验鸡进行初次免疫, 21 …

Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus

YW Chiang, MR Prausnitz, KD DeWitt… - US Patent 10,010,499, 2018 - Google Patents
The present invention relates to microneedle vaccine formulations, as well as methods of
use thereof to provide animals, including canines, protective immunity against infection and …

Production of polyclonal antibodies

LV Kendall - Making and Using Antibodies, 2006 - taylorfrancis.com
Polyclonal antibodies (pAbs) remain a widely utilized tool in research and diagnostics. They
identify specific antigens, principally protein antigens, and are used in Western blots …

CpG-induced stimulation of cytokine expression by peripheral blood mononuclear cells of foals and their dams

T Liu, J Nerren, J Murrell, V Juillard, H El Garch… - Journal of equine …, 2008 - Elsevier
A relative immunodeficiency of young foals is considered to account for the increased
susceptibility of foals to infectious diseases, including pneumonia caused by Rhodococcus …

Effects of a P-class CpG-ODN administered by intramuscular injection on plasma cytokines and on white blood cells of healthy horses

I Tosi, F Bureau, F Farnir, JM Denoix, P Lekeux… - Veterinary immunology …, 2018 - Elsevier
Abstract Cytosine-phosphate-guanosine (CpG-ODN) has been described as a potent
immunostimulatory agent in different species. No study reported the effect of a P-class CpG …

The biology of dendritic cells and their potential use in veterinary medicine

Y Vanloubbeeck, J Hostetter… - Animal health research …, 2003 - cambridge.org
Dendritic cells have been shown to be the main antigen-presenting cells in vitro and in vivo,
playing a pivotal role in the induction of both tolerance and immunity. Dendritic cells from …

Oral DNA immunization in the second trimester fetal lamb and secondary immune responses in the neonate

CH Tsang, KK Mirakhur, LA Babiuk, PJ Griebel - Vaccine, 2007 - Elsevier
We previously demonstrated that oral DNA vaccination of the third trimester fetus may be an
effective strategy to prevent vertical disease transmission despite an immature immune …

重组质粒pZeoSV2 (+)/CpG-HBcAg (ISS) 对Balb/c 小鼠的免疫作用

周健, 田德英, 许东, 陈淼, 章述军, 张振纲, 吴会玲 - 免疫学杂志, 2010 - cqvip.com
目的探讨重组质粒pZeoSV2 (+)/CpG—HBcAg (ISS) 对Balb/c 小鼠免疫的作用.
方法构建真核表达质粒pZeoSV2 (+)/CpG—HBcAg (ISSb, ISSc), 将其免疫Balb/c 小鼠, ELISA …