[HTML][HTML] Integrative toxicogenomics: Advancing precision medicine and toxicology through artificial intelligence and OMICs technology

AV Singh, V Chandrasekar, N Paudel, P Laux… - Biomedicine & …, 2023 - Elsevier
More information about a person's genetic makeup, drug response, multi-omics response,
and genomic response is now available leading to a gradual shift towards personalized …

[HTML][HTML] Advancing pharmacogenomics from single-gene to preemptive testing

CE Haidar, KR Crews, JM Hoffman… - Annual review of …, 2022 - annualreviews.org
Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

ASHP statement on the pharmacist's role in clinical pharmacogenomics

CE Haidar, N Petry, C Oxencis… - American Journal of …, 2022 - academic.oup.com
Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …

Pharmacogenomic clinical decision support: a review, how‐to guide, and future vision

DT Wake, DM Smith, S Kazi… - Clinical Pharmacology …, 2022 - Wiley Online Library
Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …

Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts

JQ Nguyen, KR Crews, BT Moore… - Journal of the …, 2023 - academic.oup.com
Thoughtful integration of interruptive clinical decision support (CDS) alerts within the
electronic health record is essential to guide clinicians on the application of …

Pharmacogenomic testing in paediatrics: Clinical implementation strategies

CIS Barker, G Groeneweg… - British journal of …, 2022 - Wiley Online Library
Pharmacogenomics (PGx) relates to the study of genetic factors determining variability in
drug response. Implementing PGx testing in paediatric patients can enhance drug safety …

Pharmacogenomic clinical decision support: a scoping review

DM Smith, DT Wake… - Clinical Pharmacology & …, 2023 - Wiley Online Library
Clinical decision support (CDS) is often cited as an essential part of pharmacogenomics
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …

Progression of precision statin prescribing for reduction of statin-associated muscle symptoms

NJ Petry, JF Baye, S Frear, K Jacobsen… - …, 2022 - Taylor & Francis
Background: Statins are among the most commonly prescribed medications, and improve
patient outcomes by lowering cholesterol levels, but also have side effects. Variations in …

[HTML][HTML] Best–worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of …

RG Salloum, JR Bishop, AL Elchynski… - Implementation science …, 2022 - Springer
Background Despite the increased demand for pharmacogenetic (PGx) testing to guide
antidepressant use, little is known about how to implement testing in clinical practice. Best …

[HTML][HTML] Should secondary pharmacogenomic variants be actively screened and reported when diagnostic genome-wide sequencing is performed in a child?

JM Friedman, Y Bombard, B Carleton, AM Issa… - Genetics in …, 2024 - Elsevier
This white paper was prepared by the Global Alliance for Genomics and Health Regulatory
and Ethics Work Stream's Pediatric Task Team to review and provide perspective with …