[HTML][HTML] Integrative toxicogenomics: Advancing precision medicine and toxicology through artificial intelligence and OMICs technology
More information about a person's genetic makeup, drug response, multi-omics response,
and genomic response is now available leading to a gradual shift towards personalized …
and genomic response is now available leading to a gradual shift towards personalized …
[HTML][HTML] Advancing pharmacogenomics from single-gene to preemptive testing
Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …
ASHP statement on the pharmacist's role in clinical pharmacogenomics
Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …
Pharmacogenomic clinical decision support: a review, how‐to guide, and future vision
Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …
Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts
JQ Nguyen, KR Crews, BT Moore… - Journal of the …, 2023 - academic.oup.com
Thoughtful integration of interruptive clinical decision support (CDS) alerts within the
electronic health record is essential to guide clinicians on the application of …
electronic health record is essential to guide clinicians on the application of …
Pharmacogenomic testing in paediatrics: Clinical implementation strategies
CIS Barker, G Groeneweg… - British journal of …, 2022 - Wiley Online Library
Pharmacogenomics (PGx) relates to the study of genetic factors determining variability in
drug response. Implementing PGx testing in paediatric patients can enhance drug safety …
drug response. Implementing PGx testing in paediatric patients can enhance drug safety …
Pharmacogenomic clinical decision support: a scoping review
Clinical decision support (CDS) is often cited as an essential part of pharmacogenomics
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …
Progression of precision statin prescribing for reduction of statin-associated muscle symptoms
NJ Petry, JF Baye, S Frear, K Jacobsen… - …, 2022 - Taylor & Francis
Background: Statins are among the most commonly prescribed medications, and improve
patient outcomes by lowering cholesterol levels, but also have side effects. Variations in …
patient outcomes by lowering cholesterol levels, but also have side effects. Variations in …
[HTML][HTML] Best–worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of …
RG Salloum, JR Bishop, AL Elchynski… - Implementation science …, 2022 - Springer
Background Despite the increased demand for pharmacogenetic (PGx) testing to guide
antidepressant use, little is known about how to implement testing in clinical practice. Best …
antidepressant use, little is known about how to implement testing in clinical practice. Best …
[HTML][HTML] Should secondary pharmacogenomic variants be actively screened and reported when diagnostic genome-wide sequencing is performed in a child?
This white paper was prepared by the Global Alliance for Genomics and Health Regulatory
and Ethics Work Stream's Pediatric Task Team to review and provide perspective with …
and Ethics Work Stream's Pediatric Task Team to review and provide perspective with …