The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

The technique of attaching the polymer polyethylene glycol (PEG), or PEGylation, has
brought more than ten protein drugs into market. The surface conjugation of PEG on proteins …

Bioconjugation methodologies have proven to play a central enabling role in the recent
development of biotherapeutics and chemical biology approaches. Recent endeavours in …

Protein–polymer conjugates are widely used as therapeutics. All Food and Drug
Administration (FDA)-approved protein conjugates are covalently linked to poly (ethylene …

Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …

The structures and synthesis of polyzwitterions (“polybetaines”) are reviewed, emphasizing
the literature of the past decade. Particular attention is given to the general challenges …

In recent years, zwitterionic materials such as poly (carboxybetaine)(pCB) and poly
(sulfobetaine)(pSB) have been applied to a broad range of biomedical and engineering …

The need for long-term treatments of chronic diseases has motivated the widespread
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …

Chemical modification of protein is an arduous but fruitful task. Many chemical methods
have been developed for such purpose by carefully balancing reactivity and selectivity. Now …

Synthetic methods in polymer chemistry have evolved tremendously during the last decade.
Nowadays more and more attention is devoted to the application of those tools in the …