Background We predicted cancer mortality figures for 2024 for the European Union (EU), its
five most populous countries, and the UK. We focused on mortality from colorectal cancer …

Fluoropyrimidine (FP) drugs are central components of combination chemotherapy
regimens for the treatment of colorectal cancer (CRC). FP-based chemotherapy has …

Although the overall incidence and mortality of colorectal cancer have declined, diagnosed
cases of young-onset colorectal cancer have increased significantly. Concerns about future …

Colorectal cancer (CRC) is one of the most fatal cancers in the United States. Although the
overall incidence and mortality rates are declining, an alarming rise in early-onset colorectal …

Simple Summary Over the last decade, early-onset colorectal cancer incidence has
continued to increase. The disparities in outcomes and overall survival (OS) between early …

Aging is a multifaceted process influenced by hereditary factors, lifestyle, and environmental
elements. As time progresses, the human body experiences degenerative changes in major …

While advances in screening have resulted in declining rates of colorectal cancer (CRC)
among adults≥ 50 years of age since the mid-2000s, the incidence of early-onset CRC …

Background There are few third-and fourth-line therapeutic options for metastatic colorectal
cancer (mCRC). In RAS/BRAF wild-type (wt) mCRC previously treated with anti-epidermal …

Colorectal cancer (CRC) is one of the deadliest cancers worldwide. Numerous studies have
reported a correlation between uric acid (UA) level and CRC risk. Here, we investigated the …

Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract.
In recent years, the age at which CRC is diagnosed has been trending younger on a global …