Natural bacteria are interesting subjects for cancer treatments owing to their unique
autonomy‐driven and hypoxic target properties. Genetically modified bacteria (such as …

Though primarily enteric pathogens, Salmonellae are responsible for a considerable yet
under-appreciated global burden of invasive disease. In South and South-East Asia, this …

Genetically modified organisms (GMOs) are increasingly used in research and industrial
systems to produce high-value pharmaceuticals, fuels and chemicals. Genetic isolation and …

The rising incidence of cancer cases worldwide generates an urgent need of novel
treatment options. Applying bacteria may represent a valuable therapeutic variant that is …

Bacteria have been investigated as anti-tumor therapeutic agents for more than a century,
since Coley first observed successful curing of a patient with inoperable cancer by injection …

The evolutionary stability of synthetic genetic circuits is key to both the understanding and
application of genetic control elements. One useful but challenging situation is a switch …

Once an engineered organism completes its task, it is useful to degrade the associated DNA
to reduce environmental release and protect intellectual property. Here we present a …

Synthetic cell therapy is a field that has broad potential for future applications in human
disease treatment. Next generation therapies will consist of engineered bacterial strains …

Genetically modified organisms (GMOs) are commonly used to produce valuable
compounds in closed industrial systems. However, their emerging applications in open …

Genetic circuits have many applications, from guiding living therapeutics to ordering process
in a bioreactor, but to be useful they have to be genetically stable and not hinder the host …