[HTML][HTML] Caenorhabditis elegans in anthelmintic research–Old model, new perspectives
SR Hahnel, CM Dilks, I Heisler, EC Andersen… - International journal for …, 2020 - Elsevier
For more than four decades, the free-living nematode Caenorhabditis elegans has been
extensively used in anthelmintic research. Classic genetic screens and heterologous …
extensively used in anthelmintic research. Classic genetic screens and heterologous …
Advances of droplet-based microfluidics in drug discovery
Introduction Drug discovery through a large number of candidates with nearly unlimited
possibilities is laborious, time-consuming, and incurs massive costs. It thus calls for fast and …
possibilities is laborious, time-consuming, and incurs massive costs. It thus calls for fast and …
Target-responsive DNA hydrogel with microfluidic chip smart readout for quantitative point-of-care testing of creatine kinase MB
M Chen, Y Wang, X Zhao, J Zhang, Y Peng, J Bai, S Li… - Talanta, 2022 - Elsevier
Swift and effective diagnosis of acute myocardial infarction (AMI) is critical to patient survival
due to its serious life-threatening effects and increasing incidence. Creatine kinase MB (CK …
due to its serious life-threatening effects and increasing incidence. Creatine kinase MB (CK …
NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans
M Rahman, H Edwards, N Birze, R Gabrilska… - Scientific reports, 2020 - nature.com
In this study, we report a microfluidic device for the whole-life culture of the nematode
Caenorhabditis elegans that allows the scoring of animal survival and health measures. This …
Caenorhabditis elegans that allows the scoring of animal survival and health measures. This …
WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans
JN Pitt, NL Strait, EM Vayndorf, BW Blue, CH Tran… - GeroScience, 2019 - Springer
Caenorhabditis elegans is a popular organism for aging research owing to its highly
conserved molecular pathways, short lifespan, small size, and extensive genetic and …
conserved molecular pathways, short lifespan, small size, and extensive genetic and …
Ce Lab, a microfluidic platform for the study of life history traits, reveals metformin and SGK-1 regulation of longevity and reproductive span
The potential to carry out high-throughput assays in a whole organism in a small space is
one of the benefits of C. elegans, but worm assays often require a large sample size with …
one of the benefits of C. elegans, but worm assays often require a large sample size with …
Microfluidics in High-Throughput Drug Screening: Organ-on-a-Chip and C. elegans-Based Innovations
S Yoon, D Kilicarslan You, U Jeong, M Lee, E Kim… - Biosensors, 2024 - mdpi.com
The development of therapeutic interventions for diseases necessitates a crucial step known
as drug screening, wherein potential substances with medicinal properties are rigorously …
as drug screening, wherein potential substances with medicinal properties are rigorously …
C. elegans: A biosensor for host–microbe interactions
C Backes, D Martinez-Martinez, F Cabreiro - Lab Animal, 2021 - nature.com
Microbes are an integral part of life on this planet. Microbes and their hosts influence each
other in an endless dance that shapes how the meta-organism interacts with its …
other in an endless dance that shapes how the meta-organism interacts with its …
Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs
S Bulterijs, BP Braeckman - Pharmaceuticals, 2020 - mdpi.com
Population aging is one of the largest challenges of the 21st century. As more people live to
advanced ages, the prevalence of age-related diseases and disabilities will increase …
advanced ages, the prevalence of age-related diseases and disabilities will increase …
Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans
D Midkiff, A San-Miguel - Molecules, 2019 - mdpi.com
The nematode Caenorhabditis elegans is a powerful model organism that has been widely
used to study molecular biology, cell development, neurobiology, and aging. Despite their …
used to study molecular biology, cell development, neurobiology, and aging. Despite their …