Background Vedolizumab registration trials were the first to include elderly patients with
moderate‐to‐severe ulcerative colitis (UC) or Crohn's disease (CD), but few real‐life data …

Despite the growing number of frail and older patients with eGFR< 45 mL/min/1.73 m2, most
studies still exclude this population, so providing guidance on the management of these …

Background: No randomized, controlled trials of screening colonoscopy have been
completed, and ongoing trials exclude persons aged 75 years or older. The Medicare …

Health research based on administrative data and the availability of regional or national
administrative databases has been increasing in recent years. We will discuss the general …

Importance The Surveillance, Epidemiology, and End Results (SEER)–Medicare linked
database may provide insights into the comparative effectiveness of oncological treatments …

Background To the extent that outcomes are mediated through negative perceptions of
generics (the nocebo effect), observational studies comparing brand-name and generic …

The number of people in their last years of life with advanced chronic conditions, palliative
care needs, and limited life prognosis due to different causes including multi-morbidity …

Objective To evaluate the risk of venous thromboembolism (VTE) in rheumatoid arthritis (RA)
patients receiving tofacitinib versus those receiving tumor necrosis factor (TNF) inhibitors …

Objective To develop and validate a novel comorbidity score (multisource comorbidity score
(MCS)) predictive of mortality, hospital admissions and healthcare costs using multiple …

The long‐term consequences of bariatric surgery on fracture risk are unclear but are likely to
vary by procedure type. In physiologic studies, Roux‐en‐Y gastric bypass (RYGB) and …