A large and complex gene on the X chromosome encodes dystrophin. Many mutations have
been described in this gene, most of which affect the expression of the muscle isoform, the …

The X-linked muscle-wasting disease Duchenne muscular dystrophy is caused by mutations
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …

Duchenne muscular dystrophy (DMD) is caused by frameshift mutations in the DMD gene
that prevent the body-wide translation of its protein product, dystrophin. Besides a severe …

Accumulating research in rodents and humans indicates that exercise benefits brain function
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …

Duchenne muscular dystrophy (DMD) is the second most commonly occurring genetically
inherited disease in humans. It is an X‐linked condition that affects approximately one in …

Background A significant component of the variation in cognitive disability that is observed in
Duchenne muscular dystrophy (DMD) is known to be under genetic regulation. In this study …

Duchenne muscular dystrophy (DMD) and the allelic disorder Becker muscular dystrophy
(BMD) are common X-linked recessive neuromuscular disorders that are associated with a …

Background Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to
dystrophin loss. Full‐length Dp427 is the primary dystrophin isoform expressed in muscle …

The presence of variable degrees of cognitive impairment, extending from severe mental
retardation to specific deficits, in patients with dystrophinopathies is a well-recognized …

Background Several cases of Becker's muscular dystrophy (BMD) have been reported,
which showed mild or subclinical skeletal muscle involvement with an overt dilated …