Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Levels of obesity have reached epidemic proportions on a global scale, which has led to
considerable increases in health problems and increased risk of several diseases, including …

Recent studies in adult and weanling rats show that dietary fat, in close association with
circulating lipids, can stimulate expression of hypothalamic peptides involved in controlling …

How the brain translates changes in internal metabolic state or perceived food quality into
alterations in feeding behavior remains poorly understood. Studies in Drosophila larvae …

Recent advances in the field of taste physiology have clarified the role of different basic taste
modalities and their implications in health and disease and proposed emphatically that there …

Adaptive trade-offs between foraging and social behavior intuitively explain many aspects of
individual decision-making. Given the intimate connection between social behavior and …

Sleep pressure increases during wake and dissipates during sleep, but the molecules and
neurons that measure homeostatic sleep pressure remain poorly understood. We present a …

The roles of the hypothalamus and particularly the lateral hypothalamus (LH) in the
regulation of inflammation and pain have been widely studied. The LH consists of a …

Objective Leptin modulates food reward via central leptin receptor (LepRb) expressing
neurons. Food reward requires stimulation of midbrain dopamine neurons and is modulated …

The rapid increase in the prevalence of overweight and obesity is becoming an important
health problem. Overweight and obesity may cause several metabolic complications …