The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

It is well established that mutations in the canonical WNT-signalling pathway play a major
role in various cancers. Critical to developing new therapeutic strategies is understanding …

Fibrolamellar carcinoma (FLC) is a lethal primary liver cancer, affecting young patients in
absence of chronic liver disease. Molecular understanding of FLC tumorigenesis is limited …

Dietary intervention in the treatment of ulcerative colitis involves, among other things,
modifications in fatty acid content and/or profile. For example, replacing saturated long chain …

Drug response prediction is important to establish personalized medicine for cancer therapy.
Model construction for predicting drug response (ie, cell viability half-maximal inhibitory …

Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
Despite recent therapeutic advancements, resistance to 5-fluorouracil (5-FU) remains a …

Abstract Microplastics (MPs) and nanoplastics (NPs) have been deemed to be newly
emerged contaminants interfering with various physiological processes closely related with …

Background In humans, two ubiquitously expressed N-myristoyltransferases, NMT1 and
NMT2, catalyze myristate transfer to proteins to facilitate membrane targeting and signaling …

Dietary exposure to acrylamide (AA) has been linked with carcinogenicity in the
gastrointestinal (GI) tract. However, epidemiologic data on AA intake in relation to cancer …

Garlic, an asexually propagated crop, is the second important bulb crop after the onion and
is used as a vegetable and medicinal plant. Abundant and diverse garlic resources have …