[HTML][HTML] Tuberculosis in an aging world

AM Olmo-Fontánez, J Turner - Pathogens, 2022 - mdpi.com
Tuberculosis (TB) is one of the leading causes of death due to its being an infectious
disease, caused by the airborne pathogen Mycobacterium tuberculosis (M. tb) …

[HTML][HTML] Evaluation of genetic mutations associated with phenotypic resistance to fluoroquinolones, bedaquiline, and linezolid in clinical Mycobacterium tuberculosis …

Q An, R Lin, Q Yang, C Wang, D Wang - Journal of Global Antimicrobial …, 2023 - Elsevier
Objectives The aim of the study was to update the classification of drugs used in multidrug-
resistant tuberculosis (MDR-TB) regimens. Group A drugs (fluoroquinolones, bedaquiline …

[HTML][HTML] Machine learning and phylogenetic analysis allow for predicting antibiotic resistance in M. tuberculosis

A Yurtseven, S Buyanova, AA Agrawal… - BMC microbiology, 2023 - Springer
Background Antimicrobial resistance (AMR) poses a significant global health threat, and an
accurate prediction of bacterial resistance patterns is critical for effective treatment and …

Rapid Diagnosis of Drug-Resistant Tuberculosis–Opportunities and Challenges

K Naidoo, R Perumal, SL Ngema, L Shunmugam… - Pathogens, 2023 - mdpi.com
Global tuberculosis (TB) eradication is undermined by increasing prevalence of emerging
resistance to available drugs, fuelling ongoing demand for more complex diagnostic and …

Opinion review of drug resistance tuberculosis in West Africa: tackling the challenges for effective control

ID Otchere, A Asante-Poku, KF Akpadja… - Frontiers in Public …, 2024 - frontiersin.org
Drug-resistant (DR) tuberculosis (TB) is a major public health concern globally, complicating
TB control and management efforts. West Africa has historically faced difficulty in combating …

Improving the diagnosis of tuberculosis: old and new laboratory tools

P Solanki, L Elton, I Honeyborne, M Park… - Expert Review of …, 2024 - Taylor & Francis
Introduction Despite recent advances in diagnostic technologies and new drugs becoming
available, tuberculosis (TB) remains a major global health burden. If detected early …

Application of BactTiter-Glo ATP bioluminescence assay for Mycobacterium tuberculosis detection

MAM Ferreira, LC Dos Santos, LGS Castellani… - … and Infectious Disease, 2024 - Elsevier
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a
global health threat, necessitating faster and more accessible diagnostic methods. This …

[HTML][HTML] Distribution of multi-drug resistant tuberculosis in Ekiti and Ondo states, Nigeria

OE Olabiyi, PA Okiki, MI Adarabioyo, OE Adebiyi… - New Microbes and New …, 2023 - Elsevier
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is one of the
top infectious killer diseases in the world. The emergence of drug-resistant MTB strains has …

Evaluation of AAICare®-TB sequence analysis tool for accurate diagnosis of drug-resistant tuberculosis: A comparative study with TB-Profiler and Mykrobe

R Singhal, S Hingane, M Bhalla, A Sharma, S Ferdosh… - Tuberculosis, 2024 - Elsevier
A rapid and comprehensive drug susceptibility test is essential for eliminating drug resistant
tuberculosis. Next generation sequencing (NGS) based susceptibility testing is being …

[HTML][HTML] Advancements in Tuberculosis Diagnostics: A Comprehensive Review of the Critical Role and Future Prospects of Xpert MTB/RIF Ultra Technology

S Yadav, G Rawal, M Jeyaraman, N Jeyaraman - Cureus, 2024 - ncbi.nlm.nih.gov
Tuberculosis remains a persistent global health challenge, demanding swift and accurate
diagnostic methods for effective treatment. The emergence of the Xpert MTB/RIF Ultra …