Interlinked and fundamental aging processes appear to be a root-cause contributor to many
disorders and diseases. One such process is cellular senescence, which entails a state of …

The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2) infection, is leading to unknown and unusual health conditions …

The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …

Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Human monocytes are divided in three major populations; classical (CD14+ CD16−), non-
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …

Multiple studies in humans and animals have demonstrated the profound impact that
exercise can have on the immune system. There is a general consensus that regular bouts …

“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …

Elderly individuals are the most susceptible to an aggressive form of coronavirus disease
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …

Exercise enhances physical performance and reduces the risk of many disorders such as
cardiovascular disease, type 2 diabetes, dementia, and cancer. Exercise characteristically …