Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In
current reproductive medicine, progesterone and its analogues play crucial roles. While the …

Steroid hormones are extremely important natural hormones in all vertebrates. They control
a wide range of physiological processes, including osmoregulation, sexual maturity …

The effluents from wastewater treatment plants (WWTPs) can be an important contamination
source for receiving waters. In this work, a comprehensive study on the impact of a WWTP …

In this paper, we evaluated the ecotoxicological potential of the 100 pharmaceuticals
expected to occur in highest quantities in the wastewater of a general hospital and a …

Background The presence of pharmaceuticals in the environment is a growing global
concern and although environmental risk assessment is required for approval of new drugs …

In aquatic ecosystems, progesterone (P4) and synthetic progestins (gestagens) originate
from excretion by humans and livestock. Synthetic progestins are used for contraception and …

Widespread detection of human pharmaceuticals in the environment, ranging between ng/L
and mg/L levels in surface waters and effluents and ng/kg to mg/kg levels in aquatic and …

This paper presents 10 recommendations for improving the European Medicines Agency's
guidance for environmental risk assessment of human pharmaceutical products. The …

Antidepressant pharmaceuticals have been reported in wastewater effluent at the nanogram
to low microgram-per-liter range, and include bupropion (BUP), fluoxetine (FLX), sertraline …

A growing number of pharmaceuticals are found in surface waters worldwide, raising
concerns about their effects on aquatic organisms and it is a major challenge to develop a …