Transcriptional and Physiological Responses Induced by Binary Mixtures of Drospirenone and Progesterone in Zebrafish (Danio rerio)

S Zucchi, L Mirbahai, S Castiglioni… - Environmental science & …, 2014 - ACS Publications
Drospirenone (DRS) is a synthetic progestin increasingly used in oral contraceptives with
similar effects to progesterone (P4). Wild fish are exposed to DRS and P4 through …

[HTML][HTML] From single chemicals to mixtures—Reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow

TJ Runnalls, N Beresford, S Kugathas… - Aquatic Toxicology, 2015 - Elsevier
The aquatic environment is polluted with thousands of chemicals. It is currently unclear
which of these pose a significant threat to aquatic biota. The typical exposure scenario is …

Occurrence, fate and removal of synthetic oral contraceptives (SOCs) in the natural environment: a review

Z Liu, JA Ogejo, A Pruden, KF Knowlton - Science of the Total Environment, 2011 - Elsevier
Synthetic oral contraceptives (SOCs) are a group of compounds with progestagenic and/or
androgenic activities, with some also possessing estrogenic activities. Recent research has …

Effect of combined exposure to lead and decabromodiphenyl ether on neurodevelopment of zebrafish larvae

B Zhu, Q Wang, X Shi, Y Guo, T Xu, B Zhou - Chemosphere, 2016 - Elsevier
The effect of combined exposure to decabromodiphenyl ether (BDE-209) and lead (Pb) on
neurodevelopment of zebrafish (Danio rerio) larvae was investigated. Zebrafish embryos …

Progestins and Antiprogestins Affect Gene Expression in Early Development in Zebrafish (Danio rerio) at Environmental Concentrations

S Zucchi, S Castiglioni, K Fent - Environmental science & …, 2012 - ACS Publications
Progesterone (P4) and synthetic progestins (gestagens) from contraceptives and hormone
therapy occur in treated wastewater and surface water, and they may have adverse effects …

Analysis of 21 progestagens in various matrices by ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) with diverse sample …

SS Liu, GG Ying, S Liu, HJ Lai, ZF Chen… - Analytical and …, 2014 - Springer
In this study, a highly sensitive and robust method using an ultra-high-performance liquid
chromatography-tandem mass spectrometry combined with solid-phase extraction and …

[PDF][PDF] Active pharmaceutical ingredients and aquatic organisms

CG Daughton, BW Brooks - Environmental contaminants in …, 2011 - api.taylorfrancis.com
The presence of active pharmaceuticals ingredients (APIs) in aquatic systems has led in
recent years to a burgeoning literature examining environmental occurrence, fate, effects …

Two synthetic progestins and natural progesterone are responsible for most of the progestagenic activities in municipal wastewater treatment plant effluents in the …

P Šauer, A Stará, O Golovko, O Valentová, A Bořík… - Water research, 2018 - Elsevier
Vast numbers of xenobiotics are known still to be present in treated municipal wastewater
treatment plant (WWTP) effluents. Some of these possess endocrine-disrupting potency and …

Assessment of multiple hormonal activities in wastewater at different stages of treatment

PA Bain, M Williams, A Kumar - Environmental toxicology and …, 2014 - Wiley Online Library
Abstract Changes in the endocrine potency of municipal wastewater at 3 wastewater
treatment plants (WWTPs) in Australia were investigated using a panel of in vitro receptor …

Effects of progesterone on reproduction and embryonic development in the fathead minnow (Pimephales promelas)

ZA DeQuattro, EJ Peissig, DS Antkiewicz… - Environmental …, 2012 - Wiley Online Library
Abstract High concentrations (375 ng/L) of the steroid hormone progesterone (P4) were
measured in snowmelt runoff associated with large livestock‐feeding operations in …