[HTML][HTML] Immunity, atherosclerosis and cardiovascular disease

J Frostegård - BMC medicine, 2013 - Springer
Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory
condition with immune competent cells in lesions producing mainly pro-inflammatory …

Systemic lupus erythematosus and cardiovascular disease

J Frostegård - Journal of Internal Medicine, 2023 - Wiley Online Library
The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment
and care, but cardiovascular disease (CVD) still remains an important clinical problem, since …

The western diet and lifestyle and diseases of civilization

P Carrera-Bastos, M Fontes-Villalba… - Research Reports in …, 2011 - Taylor & Francis
It is increasingly recognized that certain fundamental changes in diet and lifestyle that
occurred after the Neolithic Revolution, and especially after the Industrial Revolution and the …

[HTML][HTML] Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients …

AC Elkan, B Sjöberg, B Kolsrud, B Ringertz… - Arthritis research & …, 2008 - Springer
Introduction The purpose of this study was to investigate the effects of vegan diet in patients
with rheumatoid arthritis (RA) on blood lipids oxidized low-density lipoprotein (oxLDL) and …

[HTML][HTML] Increased prevalence of vulnerable atherosclerotic plaques and low levels of natural IgM antibodies against phosphorylcholine in patients with systemic lupus …

C Anania, T Gustafsson, X Hua, J Su… - Arthritis research & …, 2010 - Springer
Introduction The risk of cardiovascular disease (CVD) and atherosclerosis is reported to be
increased in systemic lupus erythematosus (SLE). We recently reported a negative …

IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus …

M Rahman, S Sing, Z Golabkesh, R Fiskesund… - Clinical …, 2016 - Elsevier
Objectives Phosphorylcholine (PC) and malondialdehyde (MDA) are generated during lipid
peroxidation and form adducts with proteins as albumin as studied herein. Atherosclerosis …

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential …

U de Faire, J Su, X Hua, A Frostegård, M Halldin… - Journal of …, 2010 - Elsevier
OBJECTIVE: We here determine the role of IgM antibodies against phosphorylcholine (anti-
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …

[HTML][HTML] The contribution of autoantibodies to inflammatory cardiovascular pathology

LA Meier, BA Binstadt - Frontiers in immunology, 2018 - frontiersin.org
Chronic inflammation and resulting tissue damage underlie the vast majority of acquired
cardiovascular disease (CVD), a general term encompassing a widely diverse array of …

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …

[HTML][HTML] Antibodies in action: the role of humoral immunity in the fight against atherosclerosis

JA Taylor, MA Hutchinson, PJ Gearhart, RW Maul - Immunity & Ageing, 2022 - Springer
The sequestering of oxidation-modified low-density lipoprotein by macrophages results in
the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes …