Background Pre‐eclampsia is associated with deficient intravascular production of
prostacyclin, a vasodilator, and excessive production of thromboxane, a vasoconstrictor and …

Background Since hypercoagulability might result in recurrent miscarriage, anticoagulant
agents could potentially increase the chance of live birth in subsequent pregnancies in …

Background Placenta-mediated pregnancy complications include pre-eclampsia, late
pregnancy loss, placental abruption, and birth of a small-for-gestational-age (SGA) neonate …

Recurrent pregnancy loss is a complex health challenge with no universally accepted
definition. Inconsistency in definitions involves not only the number of spontaneous …

To describe and analyze the benefit of immunomodulatory drugs for recurrent miscarriages
and implantation failures. The literature research was conducted in Medline, Embase and …

It is common practice in many centers to offer antithrombotic medications to women with
unexplained recurrent miscarriage, in the presence or absence of inherited thrombophilia …

Background Venous thromboembolism (VTE), although rare, is a major cause of maternal
mortality and morbidity. Some women are at increased risk of VTE during pregnancy and the …

Introduction International guidelines support the use of low molecular weight heparins for
the treatment of thromboembolism and thromboprophylaxis during pregnancy. However …

BACKGROUND Although an association between thrombophilia and pregnancy loss has
been observed in many studies, little is known about the pathophysiological mechanisms …

Background Stillbirth affects at least 2.6 million families worldwide every year and has
enduring consequences for parents and health services. Parents entering a subsequent …