Current methods for skeletal muscle tissue repair and regeneration

J Liu, D Saul, KO Böker, J Ernst… - BioMed research …, 2018 - Wiley Online Library
Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of
muscle loss, this regeneration needs interventional support. Consequently, muscle injury …

Ex vivo cell-based CRISPR/Cas9 genome editing for therapeutic applications

Y Li, Z Glass, M Huang, ZY Chen, Q Xu - Biomaterials, 2020 - Elsevier
The recently developed CRISPR/Cas9 technology has revolutionized the genome
engineering field. Since 2016, increasing number of studies regarding CRISPR therapeutics …

[HTML][HTML] Advances in aptamer-based biomarker discovery

J Huang, X Chen, X Fu, Z Li, Y Huang… - Frontiers in Cell and …, 2021 - frontiersin.org
The discovery and identification of biomarkers promote the rational and fast development of
medical diagnosis and therapeutics. Clinically, the application of ideal biomarkers still is …

[HTML][HTML] The clinical course of Duchenne muscular dystrophy in the corticosteroid treatment era: a systematic literature review

SM Szabo, RM Salhany, A Deighton… - Orphanet Journal of …, 2021 - Springer
Background Duchenne muscular dystrophy (DMD) is a severe rare progressive inherited
neuromuscular disorder, leading to loss of ambulation (LOA) and premature mortality. The …

[HTML][HTML] Biogenesis and function of extracellular vesicles in pathophysiological processes of skeletal muscle atrophy

W Wang, M Li, Z Chen, L Xu, M Chang, K Wang… - Biochemical …, 2022 - Elsevier
Pathophysiological changes of skeletal muscle occur in a variety of chronic diseases,
leading to muscle atrophy and dysfunction, which greatly affect the quality of life. Despite …

An overview of human activity recognition using wearable sensors: Healthcare and artificial intelligence

R Liu, AA Ramli, H Zhang, E Henricson… - … Conference on Internet of …, 2021 - Springer
With the rapid development of the internet of things (IoT) and artificial intelligence (AI)
technologies, human activity recognition (HAR) has been applied in a variety of domains …

European Neuromuscular Centre consensus statement on anaesthesia in patients with neuromuscular disorders

LR van den Bersselaar, L Heytens… - European journal of …, 2022 - Wiley Online Library
Background and purpose Patients with neuromuscular conditions are at increased risk of
suffering perioperative complications related to anaesthesia. There is currently little specific …

[HTML][HTML] Microalgae produce antioxidant molecules with potential preventive effects on mitochondrial functions and skeletal muscular oxidative stress

J Vignaud, C Loiseau, J Hérault, C Mayer, M Côme… - Antioxidants, 2023 - mdpi.com
In recent years, microalgae have become a source of molecules for a healthy life. Their
composition of carbohydrates, peptides, lipids, vitamins and carotenoids makes them a …

[HTML][HTML] Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases

MK Tsoumpra, S Fukumoto, T Matsumoto, S Takeda… - …, 2019 - thelancet.com
Duchenne muscular dystrophy (DMD) is an X-linked disorder characterized by progressive
muscle degeneration, caused by the absence of dystrophin. Exon skipping by antisense …

Recent advancements in understanding mammalian O-mannosylation

MO Sheikh, SM Halmo, L Wells - Glycobiology, 2017 - academic.oup.com
The post-translational glycosylation of select proteins by O-linked mannose (O-mannose or
O-man) is a conserved modification from yeast to humans and has been shown to be …