Cyclodextrins: Emerging medicines of the new millennium
SS Braga - Biomolecules, 2019 - mdpi.com
Cyclodextrins, since their discovery in the late 19th century, were mainly regarded as
excipients. Nevertheless, developments in cyclodextrin research have shown that some of …
excipients. Nevertheless, developments in cyclodextrin research have shown that some of …
Coronavirus interplay with lipid rafts and autophagy unveils promising therapeutic targets
K Fecchi, S Anticoli, D Peruzzu, E Iessi… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses are enveloped, single-stranded, positive-sense RNA viruses that can infect
animal and human hosts. The infection induces mild or sometimes severe acute respiratory …
animal and human hosts. The infection induces mild or sometimes severe acute respiratory …
The Lord of the NanoRings: Cyclodextrins and the battle against SARS-CoV-2
A handful of singular structures and laws can be observed in nature. They are not always
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …
Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry
J Lee, AJB Kreutzberger, L Odongo, EA Nelson… - Biophysical …, 2021 - cell.com
Cholesterol serves critical roles in enveloped virus fusion by modulating membrane
biophysical properties. The glycoprotein (GP) of Ebola virus (EBOV) promotes fusion in the …
biophysical properties. The glycoprotein (GP) of Ebola virus (EBOV) promotes fusion in the …
Cyclodextrin monomers and polymers for drug activity enhancement
Cyclodextrins (CDs) and cyclodextrin (CD)-based polymers are well-known complexing
agents. One of their distinctive features is to increase the quantity of a drug in a solution or …
agents. One of their distinctive features is to increase the quantity of a drug in a solution or …
Cyclic oligosaccharides as active drugs, an updated review
A Matencio, F Caldera, C Cecone, JM López-Nicolás… - Pharmaceuticals, 2020 - mdpi.com
There have been many reviews of the cyclic oligosaccharide cyclodextrin (CD) and CD-
based materials used for drug delivery, but the capacity of CDs to complex different agents …
based materials used for drug delivery, but the capacity of CDs to complex different agents …
Serinc5 restricts HIV membrane fusion by altering lipid order and heterogeneity in the viral membrane
The host restriction factor, Serinc5, incorporates into budding HIV particles and inhibits their
infection by an incompletely understood mechanism. We have previously reported that …
infection by an incompletely understood mechanism. We have previously reported that …
Chewing the fat: the conserved ability of DNA viruses to hijack cellular lipid metabolism
Viruses manipulate numerous host factors and cellular pathways to facilitate the replication
of viral genomes and the production of infectious progeny. One way in which viruses interact …
of viral genomes and the production of infectious progeny. One way in which viruses interact …
AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1
H Doshi, K Spengler, A Godbole, YS Gee… - Microbiology …, 2023 - Am Soc Microbiol
Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing
mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon …
mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon …
Apolipoprotein D facilitate the proliferation of BmNPV
S Fei, J Xia, G Ma, M Zhang, J Sun, M Feng… - International Journal of …, 2022 - Elsevier
The silkworm, Bombyx mori, a model Lepidopteran specie, is an important economic insect.
It is specifically infected by Bombyx mori nucleopolyhedrovirus (BmNPV), causing huge …
It is specifically infected by Bombyx mori nucleopolyhedrovirus (BmNPV), causing huge …