Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Major depressive disorder (MDD) is highly prevalent in adolescents and is a major risk factor
for suicidality. Recent evidence shows that accelerated cellular senescence/aging is …

In recent years, it has become known that stress in childhood, called early life stress (ELS),
affects the mental health of children, adolescents, and adults. Child maltreatment (CM) is an …

Mood disorders are the most prevalent psychiatric disorders associated with significant
disability, morbidity, and mortality. The risk of suicide is associated with severe or mixed …

Early life stress (ELS), characterized as abuse, neglect, and abandonment, can cause
several adverse consequences in the lives of affected individuals. ELS experiences can …

Environmental factors are known to interact with the genome by altering epigenetic
mechanisms regulating gene expression and contributing to the pathogenesis of psychiatric …

Exposure to stress can lead to long lasting behavioral and neurobiological consequences,
which may enhance the susceptibility for the onset of mental disorders. However, there are …

Background The transition from childhood to adolescence is characterized by enhanced
neural plasticity and a consequent susceptibility to both beneficial and adverse aspects of …

Developmental stress can detrimentally affect adult female reproductive behavior,
influencing sexual receptivity and fertility. Recent work has demonstrated neuronal nitric …