Triple-negative breast cancer accounted for 12% of breast cancers diagnosed in the United
States from 2012 to 2016, with a 5-year survival 8% to 16% lower than hormone receptor …

The number of US adults identifying as lesbian, gay, bisexual, transgender, or a different
sexual identity has doubled since 2008, and about 40% of the sexual and gender minority …

The vast majority of genome-wide association studies (GWASs) are performed in
Europeans, and their transferability to other populations is dependent on many factors (eg …

For almost two decades, equations that use serum creatinine, age, sex, and race to eGFR
have included “race” as Black or non-Black. Given considerable evidence of disparities in …

We introduce a flexible and robust simulation-based framework to infer demographic
parameters from the site frequency spectrum (SFS) computed on large genomic datasets …

Over the past 500 years, North America has been the site of ongoing mixing of Native
Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave …

Using genome-wide genotypes, we characterized the genetic structure of 103,006
participants in the Kaiser Permanente Northern California multi-ethnic Genetic Epidemiology …

North African populations are distinct from sub-Saharan Africans based on cultural,
linguistic, and phenotypic attributes; however, the time and the extent of genetic divergence …

Polygenic risk scores (PRS) use the results of genome-wide association studies (GWAS) to
predict quantitative phenotypes or disease risk at an individual level, and provide a potential …

We present a comprehensive assessment of genomic diversity in the African-American
population by studying three genotyped cohorts comprising 3,726 African-Americans from …