Role of cephalosporins in the era of Clostridium difficile infection
MH Wilcox, JD Chalmers, CE Nord… - Journal of …, 2016 - academic.oup.com
The incidence of Clostridium difficile infection (CDI) in Europe has increased markedly since
2000. Previous meta-analyses have suggested a strong association between cephalosporin …
2000. Previous meta-analyses have suggested a strong association between cephalosporin …
Safety and effectiveness of fifth generation cephalosporins for the treatment of methicillin-resistant staphylococcus aureus bloodstream infections: a narrative review …
DF Bavaro, A Belati, L Bussini, V Cento… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) bloodstream
infection (BSI) is a major issue in healthcare, since it is often associated with endocarditis or …
infection (BSI) is a major issue in healthcare, since it is often associated with endocarditis or …
Efficacy of an Optimised Bacteriophage Cocktail to Clear Clostridium difficile in a Batch Fermentation Model
Clostridium difficile infection (CDI) is a major cause of infectious diarrhea. Conventional
antibiotics are not universally effective for all ribotypes, and can trigger dysbiosis, resistance …
antibiotics are not universally effective for all ribotypes, and can trigger dysbiosis, resistance …
Microbiological profile of sarecycline, a novel targeted spectrum tetracycline for the treatment of acne vulgaris
G Zhanel, I Critchley, LY Lin… - Antimicrobial agents and …, 2019 - Am Soc Microbiol
Sarecycline is the first narrow-spectrum tetracycline-class antibiotic being developed for
acne treatment. In addition to exhibiting activity against important skin/soft tissue pathogens …
acne treatment. In addition to exhibiting activity against important skin/soft tissue pathogens …
Trehalose-Induced Remodelling of the Human Microbiota Affects Clostridioides difficile Infection Outcome in an In Vitro Colonic Model: A Pilot Study
AM Buckley, IB Moura, N Arai, W Spittal… - Frontiers in Cellular …, 2021 - frontiersin.org
Within the human intestinal tract, dietary, microbial-and host-derived compounds are used
as signals by many pathogenic organisms, including Clostridioides difficile. Trehalose has …
as signals by many pathogenic organisms, including Clostridioides difficile. Trehalose has …
Development and Validation of a Chemostat Gut Model To Study Both Planktonic and Biofilm Modes of Growth of Clostridium difficile and Human Microbiota
GS Crowther, CH Chilton, SL Todhunter, S Nicholson… - PLoS …, 2014 - journals.plos.org
The human gastrointestinal tract harbours a complex microbial community which exist in
planktonic and sessile form. The degree to which composition and function of faecal and …
planktonic and sessile form. The degree to which composition and function of faecal and …
The use of first-generation cephalosporin antibiotics, cefalexin and cefradine, is not associated with induction of simulated Clostridioides difficile infection
AM Buckley, IB Moura, J Altringham… - Journal of …, 2022 - academic.oup.com
Objectives The use of broad-spectrum cephalosporins is associated with induction of
Clostridioides difficile infection (CDI). Recent knowledge on the importance of the healthy …
Clostridioides difficile infection (CDI). Recent knowledge on the importance of the healthy …
Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro …
P Etifa, C Rodríguez, C Harmanus, IMJG Sanders… - Antibiotics, 2023 - mdpi.com
Clostridioides difficile infection (CDI) remains a significant healthcare burden. Non-toxigenic
C. difficile (NTCD) strains have shown a benefit in preventing porcine enteritis and in human …
C. difficile (NTCD) strains have shown a benefit in preventing porcine enteritis and in human …
Switching From Ceftriaxone to Cefotaxime Significantly Contributes to Reducing the Burden of Clostridioides difficile infections
S Wendt, D Ranft, AC Rodloff… - Open Forum …, 2020 - academic.oup.com
We analyzed Clostridioides difficile infection (CDI) rates and various antimicrobials'
application densities from 2013 to 2019 at Leipzig University Hospital, Germany, by using …
application densities from 2013 to 2019 at Leipzig University Hospital, Germany, by using …
Eravacycline, a novel tetracycline derivative, does not induce Clostridioides difficile infection in an in vitro human gut model
AM Buckley, J Altringham, E Clark… - Journal of …, 2021 - academic.oup.com
Objectives The approval of new antibiotics is essential to combat infections caused by
antimicrobial-resistant pathogens; however, such agents should be tested to determine their …
antimicrobial-resistant pathogens; however, such agents should be tested to determine their …