[HTML][HTML] Immunological bases of paraneoplastic cerebellar degeneration and therapeutic implications

L Yshii, C Bost, R Liblau - Frontiers in immunology, 2020 - frontiersin.org
Paraneoplastic cerebellar degeneration (PCD) is a rare immune-mediated disease that
develops mostly in the setting of neoplasia and offers a unique prospect to explore the …

Cytokine dynamics and targeted immunotherapies in autoimmune encephalitis

NL Ciano-Petersen, S Muñiz-Castrillo… - Brain …, 2022 - academic.oup.com
Autoimmune encephalitides constitute a diverse group of immune-mediated central nervous
system disorders mainly characterized by the presence of antibodies targeting neuronal or …

Serum IFN-γ-induced protein 10 (IP-10) as a biomarker for severity of acute respiratory infection in healthy adults

MS Hayney, KM Henriquez, JH Barnet, T Ewers… - Journal of Clinical …, 2017 - Elsevier
Background The inflammatory chemokine, interferon-gamma inducible protein of 10 kDa (IP-
10), is a biomarker associated with several conditions. Objectives This study investigated …

CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model

LM Yshii, CM Gebauer, B Pignolet, E Maure… - Brain, 2016 - academic.oup.com
CTLA4 is an inhibitory regulator of immune responses. Therapeutic CTLA4 blockade
enhances T cell responses against cancer and provides striking clinical results against …

Utility of CSF cytokine/chemokines as markers of active intrathecal inflammation: comparison of demyelinating, anti-NMDAR and enteroviral encephalitis

K Kothur, L Wienholt, SS Mohammad, EM Tantsis… - PLoS …, 2016 - journals.plos.org
Background Despite the discovery of CSF and serum diagnostic autoantibodies in
autoimmune encephalitis, there are still very limited CSF biomarkers for diagnostic and …

Curcumin inhibits glial scar formation by suppressing astrocyte-induced inflammation and fibrosis in vitro and in vivo

J Yuan, W Liu, H Zhu, Y Chen, X Zhang, L Li, W Chu… - Brain research, 2017 - Elsevier
Spinal cord injury (SCI) leads to glial scar formation by astrocytes, which severely hinders
neural regeneration. Curcumin (cur) can inhibit glial scar formation, but the underlying …

[HTML][HTML] Advances in biomarker-guided therapy for pediatric-and adult-onset neuroinflammatory disorders: targeting chemokines/cytokines

MR Pranzatelli - Frontiers in Immunology, 2018 - frontiersin.org
The concept and recognized components of “neuroinflammation” are expanding at the
intersection of neurobiology and immunobiology. Chemokines (CKs), no longer merely …

The role of CXCR3 in neurological diseases

YQ Zhou, DQ Liu, SP Chen, J Sun… - Current …, 2019 - ingentaconnect.com
Background: Neurological diseases have become an obvious challenge due to insufficient
therapeutic intervention. Therefore, novel drugs for various neurological disorders are in …

Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics

S Jabeen, JA Espinoza, LA Torland, M Zucknick… - …, 2019 - Taylor & Francis
Cancers elicit an immune response by modifying the microenvironment. The immune system
plays a pivotal role in cancer recognition and eradication. While the potential clinical value …

Neuropsychiatric disorders due to limbic encephalitis: Immunologic aspect

YC Kao, MI Lin, WC Weng, WT Lee - International journal of molecular …, 2020 - mdpi.com
Limbic encephalitis (LE) is a rare cause of encephalitis presenting as an acute and subacute
onset of neuropsychiatric manifestations, particularly with memory deficits and confusion as …