The influence of circular RNAs on autophagy and disease progression

Y Wang, Y Mo, M Peng, S Zhang, Z Gong, Q Yan… - Autophagy, 2022 - Taylor & Francis
Circular RNAs (circRNAs) are non-coding RNAs that have attracted considerable attention
in recent years. Owing to their distinct circular structure, circRNAs are stable in cells …

Chronic inflammation and cancer; the two sides of a coin

Q Fernandes, VP Inchakalody, T Bedhiafi, S Mestiri… - Life Sciences, 2023 - Elsevier
The correlation between chronic inflammation and cancer was initially identified in the 19th
century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors …

Old drugs, new uses: Drug repurposing in hematological malignancies

VP Kale, H Habib, R Chitren, M Patel… - Seminars in cancer …, 2021 - Elsevier
Discovery and development of novel anti-cancer drugs are expensive and time consuming.
Systems biology approaches have revealed that a drug being developed for a non-cancer …

Autophagy: novel applications of nonsteroidal anti‐inflammatory drugs for primary cancer

C Yu, W Li, J Liu, J Lu, J Feng - Cancer Medicine, 2018 - Wiley Online Library
In eukaryotic cells, autophagy is a process associated with programmed cell death. During
this process, cytoplasmic proteins and organelles are engulfed by double‐membrane …

Human non-small cell lung cancer cells can be sensitized to camptothecin by modulating autophagy

YH Chiu, SH Hsu, HW Hsu… - International …, 2018 - spandidos-publications.com
Lung cancer is a prevalent disease and is one of the leading causes of mortality worldwide.
Despite the development of various anticancer drugs, the prognosis of lung cancer is …

Unveiling autophagy complexity in leukemia: The molecular landscape and possible interactions with apoptosis and ferroptosis

YY Jung, KS Ahn, M Shen - Cancer Letters, 2024 - Elsevier
Autophagy is a self-digestion multistep process in which causes the homeostasis through
degradation of macromolecules and damaged organelles. The autophagy-mediated tumor …

Cadherins, selectins, and integrins in CAM-DR in leukemia

HN Kim, Y Ruan, H Ogana, YM Kim - Frontiers in Oncology, 2020 - frontiersin.org
The interaction between leukemia cells and the bone microenvironment is known to provide
drug resistance in leukemia cells. This phenomenon, called cell adhesion-mediated drug …

Autophagy: a necessary event during erythropoiesis

R Grosso, CM Fader, MI Colombo - Blood reviews, 2017 - Elsevier
Autophagy is a well-known cellular process involved in many physiological and pathological
processes. During erythropoiesis, autophagy plays an important role participating in the …

Celecoxib repurposing in cancer therapy: molecular mechanisms and nanomedicine-based delivery technologies

AF Khafaga, RN Shamma, A Abdeen, AM Barakat… - …, 2021 - Taylor & Francis
While cancer remains a significant global health problem, advances in cancer biology, deep
understanding of its underlaying mechanism and identification of specific molecular targets …

[HTML][HTML] The molecular mechanisms of celecoxib in tumor development

B Wen, YT Wei, LL Mu, GR Wen, K Zhao - Medicine, 2020 - journals.lww.com
Background: Clinical studies have shown that celecoxib can significantly inhibit the
development of tumors, and basic experiments and in vitro experiments also provide a …