Corneal opacity is the 5th leading cause of blindness and visual impairment globally,
affecting~ 6 million of the world population. In addition, it is responsible for 1.5–2.0 million …

Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create
an evidence-based definition and a contemporary classification system for dry eye disease …

The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity
and questionnaires reported in epidemiological studies of dry eye disease (DED). A meta …

The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

This article presents an Executive Summary of the conclusions and recommendations of the
10-chapter TFOS DEWS II report. The entire TFOS DEWS II report was published in the July …

Preservatives in multidose formulations of topical ophthalmic medications are crucial for
maintaining sterility but can be toxic to the ocular surface. Benzalkonium chloride (BAK) …