AI-based Advanced approaches and dry eye disease detection based on multi-source evidence: Cases, applications, issues, and future directions

MH Wang, L Xing, Y Pan, F Gu, J Fang… - Big Data Mining and …, 2024 - ieeexplore.ieee.org
This study explores the potential of Artificial Intelligence (AI) in early screening and
prognosis of Dry Eye Disease (DED), aiming to enhance the accuracy of therapeutic …

Gut dysbiosis is prevailing in Sjögren's syndrome and is related to dry eye severity

J Moon, SH Choi, CH Yoon, MK Kim - PloS one, 2020 - journals.plos.org
Objective To investigate gut dysbiosis in patients with Sjögren's syndrome (SS) or dry eye
syndrome (DES) compared to normal subjects and to evaluate the association of dysbiosis …

A review of the mechanism of action of cyclosporine A: the role of cyclosporine A in dry eye disease and recent formulation developments

LM Periman, FS Mah, PM Karpecki - Clinical Ophthalmology, 2020 - Taylor & Francis
Dry eye disease (DED) is a multifactorial disease of the ocular surface and tear film that has
gained awareness as a public health problem. Characteristics of DED include tear film …

BCLA CLEAR–Contact lens technologies of the future

L Jones, A Hui, CM Phan, ML Read, D Azar… - Contact lens and …, 2021 - Elsevier
Contact lenses in the future will likely have functions other than correction of refractive error.
Lenses designed to control the development of myopia are already commercially available …

Global consensus on the management of limbal stem cell deficiency

SX Deng, F Kruse, JAP Gomes, CC Chan, S Daya… - Cornea, 2020 - journals.lww.com
Purpose: In recent decades, the medical and surgical treatment of limbal stem cell deficiency
(LSCD) has evolved significantly through the incorporation of innovative pharmacological …

Design and application in delivery system of intranasal antidepressants

J Xu, J Tao, J Wang - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
One of the major reasons why depressed patients fail their treatment course is the existence
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …

Efficacy of omega-3 fatty acid supplementation for treatment of dry eye disease: a meta-analysis of randomized clinical trials

G Giannaccare, M Pellegrini, S Sebastiani, F Bernabei… - Cornea, 2019 - journals.lww.com
Purpose: To assess whether omega-3 fatty acid (FA) supplementation is more efficacious
than placebo in amelioration of signs and symptoms of dry eye disease. Methods: We …

The immunological basis of dry eye disease and current topical treatment options

LM Periman, VL Perez, DR Saban… - Journal of Ocular …, 2020 - liebertpub.com
Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular
immune response comprising innate and adaptive phases. When the ocular immune system …

TFOS Lifestyle: impact of nutrition on the ocular surface

M Markoulli, S Ahmad, J Arcot, R Arita… - The ocular …, 2023 - Elsevier
Nutrients, required by human bodies to perform life-sustaining functions, are obtained from
the diet. They are broadly classified into macronutrients (carbohydrates, lipids, and proteins) …

Intense pulsed light improves signs and symptoms of dry eye disease due to meibomian gland dysfunction: A randomized controlled study

R Toyos, NR Desai, M Toyos, SJ Dell - PLoS One, 2022 - journals.plos.org
Purpose To compare the safety and efficacy of intense pulsed light (IPL) followed by
meibomian gland expression (MGX), against monotherapy of MGX. Methods Patients with …