The changes in the brain signaling systems play an important role in etiology and
pathogenesis of Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MS), being a …

Alzheimer's disease (AD) is reaching epidemic proportions yet treatment strategies are
limited and are restricted to providing symptomatic relief for the cognitive and behavioral and …

Abstract DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the
seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective …

Abstract Metabolic syndrome (MetS) and Type 2 diabetes mellitus (T2DM) increase risk for
Alzheimer's disease (AD). The molecular mechanism for this association remains poorly …

Obesity and type 2 diabetes mellitus (T2DM) convey an increased risk for developing
dementia. The microtubule-associated protein tau is implicated in neurodegenerative …

Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) plays a central role in the
pathogenesis of diabetes. This protein has been recognized as a potential target for diabetic …

Ethnopharmacological relevance Diabetic cognitive dysfunction (DCD) is mainly one of the
complications of type 2 diabetes mellitus (T2DM) with complex and obscure pathogenesis …

Background Diabetes-associated cognition decline is one of central nervous system
complications in diabetic mellitus, while its pathogenic mechanism remains unclear. In this …

Diabetes mellitus (DM) is a metabolic disorder affecting a large number of people
worldwide. Numerous studies have demonstrated that DM can cause damage to multiple …

李林, 医学博士, 药理学教授, 博士生导师. 现任中国药理学会常务理事, 抗衰老与老年痴呆专业
委员会主任委员, 北京药理学会理事长和中国老年学学会老年医学委员会认知障碍专家委员会 …