Neuro-consequences of the spaceflight environment

SD Mhatre, J Iyer, S Puukila, AM Paul… - Neuroscience & …, 2022 - Elsevier
As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

[HTML][HTML] The vestibular contribution to the head direction signal and navigation

RM Yoder, JS Taube - Frontiers in integrative neuroscience, 2014 - frontiersin.org
Spatial learning and navigation depend on neural representations of location and direction
within the environment. These representations, encoded by place cells and head direction …

Behavior of mice aboard the International Space Station

AE Ronca, EL Moyer, Y Talyansky, M Lowe… - Scientific reports, 2019 - nature.com
Interest in space habitation has grown dramatically with planning underway for the first
human transit to Mars. Despite a robust history of domestic and international spaceflight …

Behavioral and neural subsystems of rodent exploration

SM Thompson, LE Berkowitz, BJ Clark - Learning and motivation, 2018 - Elsevier
Animals occupy territories in which resources such as food and shelter are often distributed
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …

Interactions between stress and vestibular compensation–a review

Y Saman, DE Bamiou, M Gleeson, MB Dutia - Frontiers in neurology, 2012 - frontiersin.org
Elevated levels of stress and anxiety often accompany vestibular dysfunction, while
conversely complaints of dizziness and loss of balance are common in patients with panic …

Organization of exploratory behavior under dark conditions in female and male rats

JRO Oltmanns, MH Lipton, N Adamczyk, RI Lake… - Behavioural …, 2021 - Elsevier
Sexually dimorphic performance has been observed across humans and rodents in many
spatial tasks. In general, these spatial tasks do not dissociate the use of environmental and …

Effects of acquired vestibular pathology on the organization of mouse exploratory behavior

MT Banovetz, RI Lake, AA Blackwell… - Experimental Brain …, 2021 - Springer
Rodent open field behavior is highly organized and occurs spontaneously in novel
environments. This organization is disrupted in mice with vestibular pathology, suggesting …

Otolith dysfunction alters exploratory movement in mice

PA Blankenship, LA Cherep, TN Donaldson… - Behavioural brain …, 2017 - Elsevier
The organization of rodent exploratory behavior appears to depend on self-movement cue
processing. As of yet, however, no studies have directly examined the vestibular system's …

Antisense oligonucleotide therapy rescues disruptions in organization of exploratory movements associated with Usher syndrome type 1C in mice

TN Donaldson, KT Jennings, LA Cherep… - Behavioural brain …, 2018 - Elsevier
Abstract Usher syndrome, Type 1C (USH1C) is an autosomal recessive inherited disorder in
which a mutation in the gene encoding harmonin is associated with multi-sensory deficits …

The D2 dopamine receptor and locomotor hyperactivity following bilateral vestibular deafferentation in the rat

L Stiles, Y Zheng, CL Darlington, PF Smith - Behavioural brain research, 2012 - Elsevier
Rats and mice with bilateral vestibular loss exhibit dramatic locomotor hyperactivity and
circling behaviours, which to date cannot be explained. Dysfunction of the striatal …