Objective To analyze the expression of macrophages, AIM, TGF-β1 in the kidney of IgAN
patients, and to explore the role of macrophages, AIM, TGF-β1 in the progression of renal …

CD5L, a protein expressed and secreted mainly by macrophages, is emerging as a critical
immune effector. In addition to its well-defined function as an anti-apoptotic protein, research …

Abstract Background Sirtuin 3 (SIRT3) is a crucial regulator of mitochondrial function and is
associated with injury and repair in acute kidney injury (AKI). To investigate whether …

Enhancer of zeste homolog 2 (EZH2), a well‐known methyltransferase, mediates histone H3
lysine 27 trimethylation (H3K27me3) and plays a crucial role in several kidney disease …

OBJECTIVE To assess the ability of plasma apolipoprotein (apo) A-IV (apoA4), apo C-III,
CD5 antigen-like (CD5L), complement C1q subcomponent subunit B (C1QB), complement …

Although millions of cells in the human body will undergo programmed cell death each day,
dying cells are rarely detected under homeostatic settings in vivo. The swift removal of dying …

Introduction Renal ischemia/reperfusion injury (IRI) remains one of the most diseases in
clinic. The purpose of this study was to investigate the potential role and mechanism of …

The prevalence of kidney stones is increasing and its recurrence rate within the first 5 years
is over 50%. No treatments that prevent the occurrence/recurrence of stones have reached …

CD5‐like (CD5L) is a soluble scavenger cysteine‐rich protein that modulates inflammatory
responses. We studied the involvement of CD5L in liver cancer. Immunohistochemistry (IHC) …

The mechanisms underlying acute kidney injury (AKI) and chronic kidney disease (CKD)
progression include interstitial inflammation, cellular senescence, and oxidative stress (OS) …