Single-cell genomics meets human genetics

ASE Cuomo, A Nathan, S Raychaudhuri… - Nature Reviews …, 2023 - nature.com
Single-cell genomic technologies are revealing the cellular composition, identities and
states in tissues at unprecedented resolution. They have now scaled to the point that it is …

Improved quality metrics for association and reproducibility in chromatin accessibility data using mutual information

C Roth, V Venu, V Job, N Lubbers, KY Sanbonmatsu… - BMC …, 2023 - Springer
Background Correlation metrics are widely utilized in genomics analysis and often
implemented with little regard to assumptions of normality, homoscedasticity, and …

[图书][B] Probabilistic models for structured biomedical data

A Jones - 2023 - search.proquest.com
Modern biomedical datasets—from molecular measurements of gene expression to
pathology images—hold promise for discovering new therapeutics and probing basic …