HIV is generally sexually acquired across the genital or rectal mucosa after exposure to the
genital secretions of an HIV-infected partner. Most exposures to HIV do not result in …

The mucosal surface of the female reproductive tract (FRT) is the primary site of transmission
for a plethora of sexually transmitted infections, including human immunodeficiency virus …

BACKGROUND The purpose of this study was to establish normal reference values for
several immunologic factors in semen to provide a foundation for understanding their …

Cervical cytobrush sampling is a relatively non‐invasive method for obtaining mucosal cells
from the female genital tract. To define mucosal immune cells sampled by cervical …

The mechanisms underlying the massive gastrointestinal tract CD4 T-cell depletion in
human immunodeficiency virus (HIV) infection are not well understood nor is it clear whether …

Previous studies have suggested that polyfunctional mucosal CD8+ T-cell responses may
be a correlate of protection in HIV controllers. Mucosal T-cell breadth and/or specificity may …

The intestinal tract is a lymphocyte-rich site that undergoes severe depletion of memory
CD4+ T cells within days of simian immunodeficiency virus or human immunodeficiency …

The female genital tract is the major route of heterosexual human immunodeficiency virus
(HIV) acquisition and transmission. Here, we investigated whether HIV-specific CD8 T-cell …

CD8+ T cell responses are necessary for immune control of simian immunodeficiency virus
(SIV). However, the key parameters that dictate antiviral potency remain elusive, conceivably …

Because GALT is a major portal of entry for HIV-1 and reservoir for viral replication, we
hypothesized that an ineffective cellular immune response in intestinal mucosa might …