Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

G El-Saber Batiha, A Magdy Beshbishy, L G. Wasef… - Nutrients, 2020 - mdpi.com
Medicinal plants have been used from ancient times for human healthcare as in the form of
traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an …

AMPK: a nutrient and energy sensor that maintains energy homeostasis

DG Hardie, FA Ross, SA Hawley - Nature reviews Molecular cell biology, 2012 - nature.com
AMP-activated protein kinase (AMPK) is a crucial cellular energy sensor. Once activated by
falling energy status, it promotes ATP production by increasing the activity or expression of …

Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives

FI Milagro, ML Mansego, C De Miguel… - Molecular aspects of …, 2013 - Elsevier
Nutritional factors play a life-long role in human health. Indeed, there is growing evidence
that one of the mechanisms by which nutrients and bioactive compounds affect metabolic …

A review on the effects of Allium sativum (Garlic) in metabolic syndrome

A Hosseini, H Hosseinzadeh - Journal of endocrinological investigation, 2015 - Springer
The metabolic syndrome is a common problem world-wide and includes abdominal obesity,
hypertension, dyslipidemia, and hyperglycemia disorders. It leads to insulin resistance and …

The energy balance hypothesis of obesity: do the laws of thermodynamics explain excessive adiposity?

V Torres-Carot, A Suárez-González… - European journal of …, 2022 - nature.com
In this work, we reflect upon the energy balance hypothesis of obesity. International
organizations, the general population and many scientists hold the belief that obesity is …

Allicin improves metabolism in high-fat diet-induced obese mice by modulating the gut microbiota

X Shi, X Zhou, X Chu, J Wang, B Xie, J Ge, Y Guo, X Li… - Nutrients, 2019 - mdpi.com
Allicin, naturally present in the bulbs of the lily family, has anticancer, blood pressure
lowering, blood fat lowering and diabetes improving effects. Recent studies have shown that …

[HTML][HTML] Effect of garlic powder consumption on body composition in patients with nonalcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial

D Soleimani, Z Paknahad, G Askari… - Advanced biomedical …, 2016 - journals.lww.com
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease that is becoming a public health problem in recent decades. Obesity and overweight …

Garlic essential oil protects against obesity-triggered nonalcoholic fatty liver disease through modulation of lipid metabolism and oxidative stress

YS Lai, WC Chen, CT Ho, KH Lu, SH Lin… - Journal of agricultural …, 2014 - ACS Publications
This study investigated the protective properties of garlic essential oil (GEO) and its major
organosulfur component (diallyl disulfide, DADS) against the development of nonalcoholic …

[HTML][HTML] The ethnobotanical, bioactive compounds, pharmacological activities and toxicological evaluation of garlic (Allium sativum): A review

BC Okoro, TM Dokunmu, E Okafor, IA Sokoya… - Pharmacological …, 2023 - Elsevier
Abstract Background Garlic (Allium sativum) is a medicinal plant exploited for its diverse
pharmacological benefits and used as a cooking spice globally. In traditional Chinese …

Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review

M Lu, Y Cao, J Xiao, M Song, CT Ho - Food & function, 2018 - pubs.rsc.org
Obesity is a health concern related to many metabolic disorders. In the prevention and
treatment of overweight, medicines and bariatric surgeries are major strategies but there are …