Adverse drug reactions in older adults: a narrative review of the literature

MB Zazzara, K Palmer, DL Vetrano, A Carfì… - European geriatric …, 2021 - Springer
Abstract Purpose Adverse drug reactions (ADRs) represent a common and potentially
preventable cause of unplanned hospitalization, increasing morbidity, mortality, and …

Explicit criteria as clinical tools to minimize inappropriate medication use and its consequences

D Curtin, PF Gallagher… - Therapeutic advances in …, 2019 - journals.sagepub.com
Polypharmacy and prescribing of potentially inappropriate medications (PIMs) are the key
elements of inappropriate medication use (IMU) in older multimorbid people. IMU is …

Evidence supporting the best clinical management of patients with multimorbidity and polypharmacy: a systematic guideline review and expert consensus

C Muth, JW Blom, SM Smith, K Johnell… - Journal of internal …, 2019 - Wiley Online Library
The complexity and heterogeneity of patients with multimorbidity and polypharmacy renders
traditional disease‐oriented guidelines often inadequate and complicates clinical decision …

[HTML][HTML] Potentially inadequate medications in the elderly: PRISCUS 2.0: first update of the PRISCUS list

NK Mann, T Mathes, A Sönnichsen… - Deutsches Ärzteblatt …, 2023 - ncbi.nlm.nih.gov
Background The term potentially inadequate medication (PIM) is used to describe
substances that may be unsuitable for use in the elderly and should be avoided. The …

Polypharmacy stewardship: a novel approach to tackle a major public health crisis

R Daunt, D Curtin, D O'Mahony - The Lancet Healthy Longevity, 2023 - thelancet.com
With growing global concern regarding medication-related harm, WHO launched a global
patient safety challenge, Medication Without Harm, in March, 2017. Multimorbidity …

Potentially inappropriate medication use among geriatric patients in primary care setting: A cross-sectional study using the Beers, STOPP, FORTA and MAI criteria

A Awad, O Hanna - PloS one, 2019 - journals.plos.org
Inappropriate prescribing is a risk factor for adverse drug reactions and hospitalizations in
the elderly and places a considerable burden on the healthcare system. Hence, it is …

STOPP/START criteria for potentially inappropriate prescribing in older people: version 3

D O'Mahony, A Cherubini, AR Guiteras… - European geriatric …, 2023 - Springer
Purpose STOPP/START is a physiological systems-based explicit set of criteria that attempts
to define the clinically important prescribing problems relating to potentially inappropriate …

Oral anticoagulation in the elderly and frail

RM Bauersachs, J Herold - Hämostaseologie, 2020 - thieme-connect.com
The proportion of elderly patients will increase substantially over the next decades, and both
atrial fibrillation (AF) and venous thromboembolism (VTE) are more common in the elderly …

[HTML][HTML] Artificial intelligence-supported web application design and development for reducing polypharmacy side effects and supporting rational drug use in geriatric …

SH Akyon, FC Akyon, TE Yılmaz - Frontiers in Medicine, 2023 - frontiersin.org
Introduction: The main complications of polypharmacy, which is known as the simultaneous
use of more than five drugs, are potentially inappropriate medicines (PIMs), drug-drug, and …

European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management …

N van der Velde, LJ Seppala, S Hartikainen… - European geriatric …, 2023 - Springer
Falls prevention and management in older adults is a critical global challenge. One of the
key risk factors for falls is the use of certain medications. Therefore, to prevent medication …