With the advancement in 3D bioprinting technology, cell culture methods can design 3D
environments which are both, complex and physiologically relevant. The main component in …

Biomaterials play a critical role in modern medicine as surgical guides, implants for tissue
repair, and as drug delivery systems. The emerging paradigm of precision medicine exploits …

Abstract 3D bioprinting of living cellular constructs with heterogeneity in cell types and extra
cellular matrices (ECMs) matching those of biological tissues remains challenging. Here, we …

The pharmaceutical industry is continuing to face high research and development (R&D)
costs and low overall success rates of clinical compounds during drug development. There …

Until recently, bioprinting was largely limited to highly interdisciplinary research teams, as
the process requires significant input from specialists in the fields of materials science …

Investigative toxicology describes the de-risking and mechanistic elucidation of toxicities,
supporting early safety decisions in the pharmaceutical industry. Recently, investigative …

Abstract 3D bioprinting is an additive biomanufacturing technology having potential to fast-
forward the translational research, as it has the capability to fabricate artificial tissues and …

The liver executes 500+ functions, such as protein synthesis, xenobiotic metabolism, bile
production, and metabolism of carbohydrates/fats/proteins. Such functions can be severely …

Liver fibrosis is the late consequence of chronic liver inflammation which could eventually
lead to cirrhosis, and liver failure. Among various etiological factors, activated hepatic …

Recent progress in the fields of tissue engineering, micro-electro mechanical systems, and
materials science have greatly improved cell culture systems, which were traditionally …