Classification, processing, and applications of bioink and 3D bioprinting: A detailed review
With the advancement in 3D bioprinting technology, cell culture methods can design 3D
environments which are both, complex and physiologically relevant. The main component in …
environments which are both, complex and physiologically relevant. The main component in …
Additive manufacturing of precision biomaterials
EA Guzzi, MW Tibbitt - Advanced materials, 2020 - Wiley Online Library
Biomaterials play a critical role in modern medicine as surgical guides, implants for tissue
repair, and as drug delivery systems. The emerging paradigm of precision medicine exploits …
repair, and as drug delivery systems. The emerging paradigm of precision medicine exploits …
3D bioprinting of bicellular liver lobule-mimetic structures via microextrusion of cellulose nanocrystal-incorporated shear-thinning bioink
Abstract 3D bioprinting of living cellular constructs with heterogeneity in cell types and extra
cellular matrices (ECMs) matching those of biological tissues remains challenging. Here, we …
cellular matrices (ECMs) matching those of biological tissues remains challenging. Here, we …
Recommended guidelines for developing, qualifying, and implementing complex in vitro models (CIVMs) for drug discovery
JE Ekert, J Deakyne, P Pribul-Allen… - … the Science of Drug …, 2020 - journals.sagepub.com
The pharmaceutical industry is continuing to face high research and development (R&D)
costs and low overall success rates of clinical compounds during drug development. There …
costs and low overall success rates of clinical compounds during drug development. There …
3D bioprinting: the emergence of programmable biodesign
S Correia Carreira, R Begum… - Advanced healthcare …, 2020 - Wiley Online Library
Until recently, bioprinting was largely limited to highly interdisciplinary research teams, as
the process requires significant input from specialists in the fields of materials science …
the process requires significant input from specialists in the fields of materials science …
Optimizing drug discovery by investigative toxicology: current and future trends
M Beilmann, H Boonen, A Czich, G Dear… - ALTEX-Alternatives to …, 2019 - altex.org
Investigative toxicology describes the de-risking and mechanistic elucidation of toxicities,
supporting early safety decisions in the pharmaceutical industry. Recently, investigative …
supporting early safety decisions in the pharmaceutical industry. Recently, investigative …
3D bioprinting: recent trends and challenges
Abstract 3D bioprinting is an additive biomanufacturing technology having potential to fast-
forward the translational research, as it has the capability to fabricate artificial tissues and …
forward the translational research, as it has the capability to fabricate artificial tissues and …
[HTML][HTML] Emerging trends in modeling human liver disease in vitro
GH Underhill, SR Khetani - APL bioengineering, 2019 - pubs.aip.org
The liver executes 500+ functions, such as protein synthesis, xenobiotic metabolism, bile
production, and metabolism of carbohydrates/fats/proteins. Such functions can be severely …
production, and metabolism of carbohydrates/fats/proteins. Such functions can be severely …
In vitro modeling of liver fibrosis in 3D microtissues using scalable micropatterning system
E Zahmatkesh, A Othman, B Braun, R Aspera… - Archives of …, 2022 - Springer
Liver fibrosis is the late consequence of chronic liver inflammation which could eventually
lead to cirrhosis, and liver failure. Among various etiological factors, activated hepatic …
lead to cirrhosis, and liver failure. Among various etiological factors, activated hepatic …
Reconstituted human organ models as a translational tool for human organ response: definition, expectations, cases, and strategies for implementation in drug …
K Tetsuka, M Ohbuchi, T Kawabe, T Goto… - Biological and …, 2020 - jstage.jst.go.jp
Recent progress in the fields of tissue engineering, micro-electro mechanical systems, and
materials science have greatly improved cell culture systems, which were traditionally …
materials science have greatly improved cell culture systems, which were traditionally …