Naturally occurring chalcones and their biological activities

Z Rozmer, P Perjési - Phytochemistry reviews, 2016 - Springer
The aim of this review is to summarize the various naturally occurring chalcone compounds
which have been isolated from different plants. Chalcones considered as obligate …

[HTML][HTML] Phenolic compounds in Lycium berry: Composition, health benefits and industrial applications

Y Jiang, Z Fang, W Leonard, P Zhang - Journal of Functional Foods, 2021 - Elsevier
This review provides a comprehensive summary of phenolic compounds in Lycium berry,
focusing on their composition, functionalities, potential health benefits, industrial …

[HTML][HTML] Microwave-assisted synthesis, antioxidant activity, docking simulation, and DFT analysis of different heterocyclic compounds

MA Shalaby, AM Fahim, SA Rizk - Scientific Reports, 2023 - nature.com
In this investigation, pressure microwave irradiation was used to clarify the activity of 1-(2-
hydroxyphenyl)-3-(4-methylphenyl) prop-2-en-1-one (3) towards several active methylene …

[HTML][HTML] Metabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting …

M Eichenberger, BJ Lehka, C Folly, D Fischer… - Metabolic …, 2017 - Elsevier
Dihydrochalcones are plant secondary metabolites comprising molecules of significant
commercial interest as antioxidants, antidiabetics, or sweeteners. To date, their …

[HTML][HTML] Phloretin, as a potent anticancer compound: from chemistry to cellular interactions

HS Tuli, P Rath, A Chauhan, S Ramniwas, K Vashishth… - Molecules, 2022 - mdpi.com
Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in
apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties …

Phytochemicals and their potential usefulness in inflammatory bowel disease

SJ Somani, KP Modi, AS Majumdar… - Phytotherapy …, 2015 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract with unclear etiology, namely ulcerative colitis and Crohn's disease. Various drug …

An ongoing journey of chalcone analogues as single and multi-target ligands in the field of Alzheimer's disease: A review with structural aspects

P Sharma, M Singh - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative disorder with
progressive dementia and cognitive impairment. AD poses severe health challenge in …

[HTML][HTML] Protective effects of flavonoids against mitochondriopathies and associated pathologies: focus on the predictive approach and personalized prevention

L Koklesova, A Liskova, M Samec, K Zhai… - International Journal of …, 2021 - mdpi.com
Multi-factorial mitochondrial damage exhibits a “vicious circle” that leads to a progression of
mitochondrial dysfunction and multi-organ adverse effects. Mitochondrial impairments …

Implications of flavonoids as potential modulators of cancer neovascularity

A Liskova, L Koklesova, M Samec, E Varghese… - Journal of cancer …, 2020 - Springer
Purpose The formation of new blood vessels from previous ones, angiogenesis, is critical in
tissue repair, expansion or remodeling in physiological processes and in various …

[HTML][HTML] Exploring aurone derivatives as potential human pancreatic lipase inhibitors through molecular docking and molecular dynamics simulations

PTV Nguyen, HA Huynh, DV Truong, TD Tran, CVT Vo - Molecules, 2020 - mdpi.com
Inhibition of human pancreatic lipase, a crucial enzyme in dietary fat digestion and
absorption, is a potent therapeutic approach for obesity treatment. In this study, human …