Defining and combating antibiotic resistance from One Health and Global Health perspectives

S Hernando-Amado, TM Coque, F Baquero… - Nature …, 2019 - nature.com
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

DW Kim, CJ Cha - Experimental & molecular medicine, 2021 - nature.com
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …

Forecasting the dissemination of antibiotic resistance genes across bacterial genomes

MMH Ellabaan, C Munck, A Porse, L Imamovic… - Nature …, 2021 - nature.com
Antibiotic resistance spreads among bacteria through horizontal transfer of antibiotic
resistance genes (ARGs). Here, we set out to determine predictive features of ARG transfer …

Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome

SC Forster, J Liu, N Kumar, EL Gulliver… - Nature …, 2022 - nature.com
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …

Population-level impacts of antibiotic usage on the human gut microbiome

K Lee, S Raguideau, K Sirén, F Asnicar… - Nature …, 2023 - nature.com
The widespread usage of antimicrobials has driven the evolution of resistance in pathogenic
microbes, both increased prevalence of antimicrobial resistance genes (ARGs) and their …

A review of current bacterial resistance to antibiotics in food animals

C Xu, L Kong, H Gao, X Cheng, X Wang - Frontiers in Microbiology, 2022 - frontiersin.org
The overuse of antibiotics in food animals has led to the development of bacterial resistance
and the widespread of resistant bacteria in the world. Antibiotic-resistant bacteria (ARB) and …

Evolutionary pathways and trajectories in antibiotic resistance

F Baquero, JL Martinez, V F. Lanza… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

At the nexus of antibiotics and metals: the impact of Cu and Zn on antibiotic activity and resistance

K Poole - Trends in microbiology, 2017 - cell.com
Environmental influences on antibiotic activity and resistance can wreak havoc with in vivo
antibiotic efficacy and, ultimately, antimicrobial chemotherapy. In nature, bacteria encounter …

Metagenome-assembled genomes and gene catalog from the chicken gut microbiome aid in deciphering antibiotic resistomes

Y Feng, Y Wang, B Zhu, GF Gao, Y Guo… - Communications biology, 2021 - nature.com
Gut microbial reference genomes and gene catalogs are necessary for understanding the
chicken gut microbiome. Here, we assembled 12,339 microbial genomes and constructed a …

A review of the distribution of antibiotics in water in different regions of China and current antibiotic degradation pathways

C Liu, L Tan, L Zhang, W Tian, L Ma - Frontiers in environmental …, 2021 - frontiersin.org
Antibiotic pollution is becoming an increasingly serious threat in different regions of China.
The distribution of antibiotics in water sources varies significantly in time and space …