The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

Around 0.75 million babies worldwide suffer from moderate or severe hypoxic-ischemic
encephalopathy (HIE) each year resulting in around 400,000 babies with …

Summary Glucagon-like peptide-1 (GLP-1) is a signal peptide released from
enteroendocrine cells of the lower intestine. GLP-1 exerts anorectic and antimotility actions …

Compositional oscillations of the gut microbiome are essential for normal peripheral
circadian rhythms, both of which are disrupted in diet-induced obesity (DIO). Although time …

Although the increasing studies have corroborated the biological activities and great market
utilization value of polysaccharide fractions derived from Polygonati rhizome, a well-known …

Despite being a successful diabetes type 2 drug for more than a half-century in Europe, the
mode of action of metformin is still debated. It is the purpose of this review to inform the …

Background Obesity in both adults and children is a primary health concern that can lead to
many complications at a young age, including insulin resistance, type 2 diabetes, and other …

Here, we provide a focused review of the evidence for the roles of the vagus nerve in
mediating the regulatory effects of peripherally and centrally produced GLP‐1 on eating …

Harnessing the translational potential of the GLP-1/GLP-1R system in pancreatic beta cells
has led to the development of established GLP-1R-based therapies for the long-term …

Glucagon-like peptide-1 (GLP-1) secreted from enteroendocrine L-cells is a pleiotropic
hormone with beneficial potential related to islet function, diet control, glucose homeostasis …