A community-based transcriptomics classification and nomenclature of neocortical cell types

R Yuste, M Hawrylycz, N Aalling, A Aguilar-Valles… - Nature …, 2020 - nature.com
To understand the function of cortical circuits, it is necessary to catalog their cellular
diversity. Past attempts to do so using anatomical, physiological or molecular features of …

New insights into the classification and nomenclature of cortical GABAergic interneurons

J DeFelipe, PL López-Cruz… - Nature Reviews …, 2013 - nature.com
A systematic classification and accepted nomenclature of neuron types is much needed but
is currently lacking. This article describes a possible taxonomical solution for classifying …

[HTML][HTML] Shared and distinct transcriptomic cell types across neocortical areas

B Tasic, Z Yao, LT Graybuck, KA Smith, TN Nguyen… - Nature, 2018 - nature.com
The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …

[HTML][HTML] Reconstruction and simulation of neocortical microcircuitry

H Markram, E Muller, S Ramaswamy, MW Reimann… - Cell, 2015 - cell.com
We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of
juvenile rat. The reconstruction uses cellular and synaptic organizing principles to …

Training and operation of an integrated neuromorphic network based on metal-oxide memristors

M Prezioso, F Merrikh-Bayat, BD Hoskins, GC Adam… - Nature, 2015 - nature.com
Despite much progress in semiconductor integrated circuit technology, the extreme
complexity of the human cerebral cortex, with its approximately 1014 synapses, makes the …

4K-memristor analog-grade passive crossbar circuit

H Kim, MR Mahmoodi, H Nili, DB Strukov - Nature communications, 2021 - nature.com
The superior density of passive analog-grade memristive crossbar circuits enables storing
large neural network models directly on specialized neuromorphic chips to avoid costly off …

Constant sub-second cycling between representations of possible futures in the hippocampus

K Kay, JE Chung, M Sosa, JS Schor, MP Karlsson… - Cell, 2020 - cell.com
Cognitive faculties such as imagination, planning, and decision-making entail the ability to
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …

Astrocytes modulate sensory-evoked neuronal network activity

J Lines, ED Martin, P Kofuji, J Aguilar… - Nature communications, 2020 - nature.com
While neurons principally mediate brain function, astrocytes are emerging as cells with
important neuromodulatory actions in brain physiology. In addition to homeostatic roles …

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

Y Shi, P Kirwan, J Smith, HPC Robinson… - Nature …, 2012 - nature.com
Efforts to study the development and function of the human cerebral cortex in health and
disease have been limited by the availability of model systems. Extrapolating from our …

2D and 3D stem cell models of primate cortical development identify species-specific differences in progenitor behavior contributing to brain size

T Otani, MC Marchetto, FH Gage, BD Simons… - Cell stem cell, 2016 - cell.com
Variation in cerebral cortex size and complexity is thought to contribute to differences in
cognitive ability between humans and other animals. Here we compare cortical progenitor …