Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Prevention of acute exacerbations of COPD: American college of chest physicians and Canadian thoracic society guideline

GJ Criner, J Bourbeau, RL Diekemper, DR Ouellette… - Chest, 2015 - Elsevier
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …

Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre …

FJ Martinez, PMA Calverley, UM Goehring, M Brose… - The Lancet, 2015 - thelancet.com
Background Roflumilast reduces exacerbations in patients with severe chronic obstructive
pulmonary disease. Its effect in patients using fixed combinations of inhaled corticosteroids …

Withdrawal of inhaled corticosteroids in COPD patients: rationale and algorithms

S Avdeev, Z Aisanov, V Arkhipov… - … Journal of Chronic …, 2019 - Taylor & Francis
Observational studies indicate that overutilization of inhaled corticosteroids (ICS) is common
in patients with chronic obstructive pulmonary disease (COPD). Overprescription and the …

Isorhamnetin alleviates airway inflammation by regulating the Nrf2/Keap1 pathway in a mouse model of COPD

Y Xu, J Li, Z Lin, W Liang, L Qin, J Ding… - Frontiers in …, 2022 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a severely disabling chronic lung disease
characterized by persistent airway inflammation, which leads to limited expiratory airflow that …

Safety of inhaled corticosteroids for treating chronic obstructive pulmonary disease

MG Matera, V Cardaci, M Cazzola… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The frequent use of inhaled corticosteroids (ICSs), especially at higher doses,
has been accompanied by concern about both systemic and local side effects. Patients …

Oligonucleotide therapy for obstructive and restrictive respiratory diseases

W Liao, J Dong, HY Peh, LH Tan, KS Lim, L Li… - Molecules, 2017 - mdpi.com
Inhaled oligonucleotide is an emerging therapeutic modality for various common respiratory
diseases, including obstructive airway diseases like asthma and chronic obstructive …

[HTML][HTML] Stepwise withdrawal of inhaled corticosteroids in COPD patients receiving dual bronchodilation: WISDOM study design and rationale

H Magnussen, H Watz, A Kirsten, M Decramer… - Respiratory …, 2014 - Elsevier
Long-acting bronchodilators in combination with inhaled corticosteroids (ICS) are
recommended to decrease the risk of recurrent exacerbations in patients with Global …

Modified Bushen Yiqi Formula mitigates pulmonary inflammation and airway remodeling by inhibiting neutrophils chemotaxis and IL17 signaling pathway in rats with …

Q Kong, B Wang, Y Zhong, W Chen, J Sun, B Liu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Chronic obstructive pulmonary disease (COPD) is a major
global health concern characterized by pulmonary inflammation and airway remodeling …

Inhaled corticosteroids for chronic obstructive pulmonary disease

M Cazzola, P Rogliani, L Novelli… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Current guidelines recommend the use of inhaled long-acting bronchodilators,
inhaled corticosteroids (ICSs) and their combinations for maintenance treatment of moderate …