[HTML][HTML] Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance
L Yuan, ZY Xu, SM Ruan, S Mo, JJ Qin, XD Cheng - Molecular cancer, 2020 - Springer
Gastric cancer is a deadly disease and remains the third leading cause of cancer-related
death worldwide. The 5-year overall survival rate of patients with early-stage localized …
death worldwide. The 5-year overall survival rate of patients with early-stage localized …
[HTML][HTML] Targeting CLDN18. 2 in cancers of the gastrointestinal tract: New drugs and new indications
J Chen, Z Xu, C Hu, S Zhang, M Zi, L Yuan… - Frontiers in …, 2023 - frontiersin.org
Cancers of the gastrointestinal (GI) tract greatly contribute to the global cancer burden and
cancer-related death. Claudin-18.2 (CLDN18. 2), a transmembrane protein, is a major …
cancer-related death. Claudin-18.2 (CLDN18. 2), a transmembrane protein, is a major …
[HTML][HTML] circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2
L Peng, H Sang, S Wei, Y Li, D Jin, X Zhu, X Li, Y Dang… - Molecular cancer, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs)
and can modulate gene expression by binding to miRNAs; further, circRNAs have been …
and can modulate gene expression by binding to miRNAs; further, circRNAs have been …
[HTML][HTML] SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway
S Tian, P Peng, J Li, H Deng, N Zhan, Z Zeng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
In this study, we investigated the role of SERPINH1 in gastric cancer (GC) progression. GC
patient tissues show significantly higher SERPINH1 mRNA and protein levels than normal …
patient tissues show significantly higher SERPINH1 mRNA and protein levels than normal …
[HTML][HTML] Emerging roles of circular RNAs in gastric cancer metastasis and drug resistance
X Wang, J Zhang, G Cao, J Hua, G Shan… - Journal of Experimental & …, 2022 - Springer
Gastric cancer (GC) is an aggressive malignancy with a high mortality rate and poor
prognosis, primarily caused by metastatic lesions. Improved understanding of GC metastasis …
prognosis, primarily caused by metastatic lesions. Improved understanding of GC metastasis …
[HTML][HTML] ALDH1: A potential therapeutic target for cancer stem cells in solid tumors
Y Wei, Y Li, Y Chen, P Liu, S Huang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Solid tumors can be divided into benign solid tumors and solid malignant tumors in the
academic community, among which malignant solid tumors are called cancers. Cancer is …
academic community, among which malignant solid tumors are called cancers. Cancer is …
[HTML][HTML] Wnt/β-catenin-driven EMT regulation in human cancers
W Xue, L Yang, C Chen, M Ashrafizadeh, Y Tian… - Cellular and Molecular …, 2024 - Springer
Metastasis accounts for 90% of cancer-related deaths among the patients. The
transformation of epithelial cells into mesenchymal cells with molecular alterations can occur …
transformation of epithelial cells into mesenchymal cells with molecular alterations can occur …
M6A demethylase fat mass and obesity‐associated protein regulates cisplatin resistance of gastric cancer by modulating autophagy activation through ULK1
Y Zhang, L Gao, W Wang, T Zhang, F Dong… - Cancer …, 2022 - Wiley Online Library
Drug resistance is an important factor for treatment failure of gastric cancer. N6‐
methyladenosine (m6A) is the predominant mRNA internal modification in eukaryotes. The …
methyladenosine (m6A) is the predominant mRNA internal modification in eukaryotes. The …
Research progress on the circRNA/lncRNA-miRNA-mRNA axis in gastric cancer
X Zeng, J Xiao, X Bai, Y Liu, M Zhang, J Liu… - … -Research and Practice, 2022 - Elsevier
Gastric cancer is one of the most common malignant tumours worldwide. Genetic and
epigenetic alterations are key factors in gastric carcinogenesis and drug resistance to …
epigenetic alterations are key factors in gastric carcinogenesis and drug resistance to …
Induction of fibroblast growth factor receptor 4 by helicobacter pylori via signal transducer and activator of transcription 3 with a feedforward activation loop involving …
Background & Aims Helicobacter pylori (H pylori) infection is the main risk factor for gastric
cancer. The role of fibroblast growth factor receptors (FGRFs) in H pylori-mediated gastric …
cancer. The role of fibroblast growth factor receptors (FGRFs) in H pylori-mediated gastric …