Intravascular mesenchymal stromal/stem cell therapy product diversification: time for new clinical guidelines

G Moll, JA Ankrum, J Kamhieh-Milz, K Bieback… - Trends in molecular …, 2019 - cell.com
Intravascular infusion is the most popular route for therapeutic multipotent mesenchymal
stromal/stem cell (MSC) delivery in hundreds of clinical trials. Meta-analysis has …

The importance of the endothelium in atherothrombosis and coronary stenting

F Otsuka, AV Finn, SK Yazdani, M Nakano… - Nature Reviews …, 2012 - nature.com
Deployment of drug-eluting stents instead of bare-metal stents has dramatically reduced
restenosis rates, but rates of very late stent thrombosis (> 1 year postimplantation) have …

Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs

T Won, MK Wood, DM Hughes, MV Talor, Z Ma… - …, 2022 - thelancet.com
Background Thromboembolism is a life-threatening manifestation of coronavirus disease
2019 (COVID-19). We investigated a dysfunctional phenotype of vascular endothelial cells …

Are therapeutic human mesenchymal stromal cells compatible with human blood?

G Moll, I Rasmusson-Duprez, L von Bahr… - Stem …, 2012 - academic.oup.com
Multipotent mesenchymal stromal cells (MSCs) are tested in numerous clinical trials.
Questions have been raised concerning fate and function of these therapeutic cells after …

[HTML][HTML] Lipopolysaccharide signaling in endothelial cells

SM Dauphinee, A Karsan - Laboratory investigation, 2006 - Elsevier
Sepsis is the systemic immune response to severe bacterial infection. The innate immune
recognition of bacterial and viral products is mediated by a family of transmembrane …

Regulation of the cerebral circulation: role of endothelium and potassium channels

FM Faraci, DD Heistad - Physiological reviews, 1998 - journals.physiology.org
Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of
Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998.—Several new …

Emerging role of vitamin D and its associated molecules in pathways related to pathogenesis of thrombosis

S Mohammad, A Mishra, MZ Ashraf - Biomolecules, 2019 - mdpi.com
Vitamin D, besides having an essential role in calcium and bone metabolism, also acts as a
mediator of many non-calcemic effects through modulations of several biological responses …

Mechanisms of coronary thrombosis in cigarette smoke exposure

RS Barua, JA Ambrose - Arteriosclerosis, thrombosis, and vascular …, 2013 - Am Heart Assoc
Acute rupture or erosion of a coronary atheromatous plaque and subsequent coronary artery
thrombosis cause the majority of sudden cardiac deaths and myocardial infarctions …

A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties

SG Wise, MJ Byrom, A Waterhouse, PG Bannon… - Acta biomaterialia, 2011 - Elsevier
Small-diameter synthetic vascular graft materials fail to match the patency of human tissue
conduits used in vascular bypass surgery. The foreign surface retards endothelialization and …

Hemostatic biomaterials to halt non-compressible hemorrhage

S Jiang, S Liu, S Lau, J Li - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Non-compressible hemorrhage is an unmet clinical challenge, which occurs in inaccessible
sites in the body where compression cannot be applied to stop bleeding. Current treatments …