Polyphenols derived from fruits, vegetables, and plants are bioactive compounds potentially
beneficial to human health. Notably, compounds such as quercetin, curcumin …

Age-related gastrointestinal decline contributes to whole-organism frailty and mortality.
Genistein is known to have beneficial effects on age-related diseases, but its precise role in …

Lipid peroxidation (LP) leads to changes in the fluidity and permeability of cell membranes,
affecting normal cellular function and potentially triggering apoptosis or necrosis. This …

A computational protocol aimed to design new antioxidants with versatile behavior is
presented. It is called Computer-Assisted Design of Multifunctional Antioxidants and is …

It has been proposed that oxidative stress is a pathogenic mechanism to induce cytotoxicity
and to cause cardiovascular and neuronal diseases. At present, natural compounds such as …

Small molecules are being explored intensively for their applications as therapeutic
molecules in the management of metabolic and neurological disorders. The natural small …

Over the last three decades, neurodegenerative diseases have received increasing
attention due to their frequency in the aging population and the social and economic …

Our research aimed to develop an amorphous solid dispersion (ASD) of myricetin (MYR)
with Polyvinylpyrrolidone K30 (PVP30) to enhance its solubility, dissolution rate, antioxidant …

BACKGROUND: Hylocereus undatus is a traditional medicinal plant known for its medicinal,
nutritional and commercial uses. OBJECTIVE: To address the anti-aging and …

Aging is associated with alterations in gut function, including intestinal inflammation, leaky
gut, and impaired epithelial regeneration. Rejuvenating the aged gut is imperative to extend …