Multifaceted functions of Drp1 in hypoxia/ischemia-induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy

S Hao, H Huang, RY Ma, X Zeng, CY Duan - Military Medical Research, 2023 - Springer
Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings.
Mitochondria are sensitive organelles that are readily damaged following ischemia and …

Control of mitochondrial activity by the ubiquitin code in health and cancer

L Rinaldi, E Senatore, R Iannucci, F Chiuso… - Cells, 2023 - mdpi.com
Cellular homeostasis is tightly connected to the broad variety of mitochondrial functions. To
stay healthy, cells need a constant supply of nutrients, energy production and antioxidants …

Casting Light on the Janus-Faced HMG-CoA Reductase Degradation Protein 1: A Comprehensive Review of Its Dualistic Impact on Apoptosis in Various Diseases

RK Moghadam, A Daraei, M Haddadi, A Mardi… - Molecular …, 2024 - Springer
Nowadays, it is well recognized that apoptosis, as a highly regulated cellular process, plays
a crucial role in various biological processes, such as cell differentiation. Dysregulation of …