High-dose naloxone formulations are not as essential as we thought

PM Lemen, DP Garrett, E Thompson, M Aho… - Harm Reduction …, 2024 - Springer
Naloxone is an effective FDA-approved opioid antagonist for reversing opioid overdoses.
Naloxone is available to the public and can be administered through intramuscular (IM) …

Opioid use, prescribing and fatal overdose patterns among racial/ethnic minorities in the United States: A scoping review and conceptual risk environment model

JM Ezell, MT Pho, BP Ajayi, E Simek… - Drug and Alcohol …, 2024 - Wiley Online Library
Issues To date, there has been no synthesis of research addressing the scale and nuances
of the opioid epidemic in racial/ethnic minority populations in the United States that …

National and regional trends in fentanyl seizures in the United States, 2017–2023

JJ Palamar, N Fitzgerald, TH Carr, LB Cottler… - International Journal of …, 2024 - Elsevier
Background Rates of synthetic opioid-related deaths over time and across regions have
been compared within the US, but other indicator data could help inform prevention and …

Association between willingness to use an overdose prevention center and probation or parole status among people who use drugs in Rhode Island

M Tan, C Park, J Goldman, KB Biello, J Buxton… - Harm reduction …, 2024 - Springer
Abstract Background Overdose prevention centers (OPCs) are being implemented in the
United States as a strategy to reduce drug-related mortality and morbidity. Previous studies …

Effects of inhaled low-concentration xenon gas on naltrexone-precipitated withdrawal symptoms in morphine-dependent mice

MJ Kaufman, EG Meloni, AN Qrareya… - Drug and Alcohol …, 2024 - Elsevier
Background Opioid withdrawal symptoms (OWS) are highly aversive and prompt
unprescribed opioid use, which increases morbidity, mortality, and, among individuals being …

COVID-19 vaccination uptake and determinants of booster vaccination among persons who inject drugs in New York City

M Khezri, C McKnight, CA Weng, S Kimball… - Plos one, 2024 - journals.plos.org
Background Persons who inject drugs (PWID) may be unengaged with healthcare services
and face an elevated risk of severe morbidity and mortality associated with COVID-19 due to …

Factors associated with gaps in naloxone knowledge: evidence from a 2022 great plains survey

S Cooper-Ohm, P Habecker, R Humeniuk… - Harm Reduction …, 2024 - Springer
Background The rising prevalence of fast-acting opioids in the USA suggests the increased
need for non-professional first responder administration of naloxone. Effective administration …

[HTML][HTML] Barriers to, and Facilitators of, Checking Drugs for Adulterants in the Era of Fentanyl and Xylazine: Qualitative Study

ID Aronson, MA Ardouin-Guerrier, JE Baus… - JMIR Formative …, 2024 - formative.jmir.org
Background: Overdose deaths continue to reach new records in New York City and
nationwide, largely driven by adulterants such as fentanyl and xylazine in the illicit drug …

Differential risks of syringe service program participants in Central Ohio: a latent class analysis

KJ Moon, I Bryant, A Trinh, KA Hasenstab… - Harm Reduction …, 2023 - Springer
Background Significant heterogeneity exists among people who use drugs (PWUD). We
identify distinct profiles of syringe service program (SSP) clients to (a) evaluate differential …

Prevalence and drug use correlates of inadvertent fentanyl exposure among individuals misusing drugs in seven US states

S Magura, MJ Lee-Easton, R Abu-Obaid… - Journal of Addictive …, 2023 - Taylor & Francis
Background: Fentanyl has emerged as the leading cause of fatal drug overdoses in the US
Individuals misusing drugs may not always be aware of exposure to fentanyl. Objectives: To …