Chimerism monitoring techniques after hematopoietic stem cell transplantation: an overview of the last 15 years of innovations

P Tozzo, A Delicati, R Zambello, L Caenazzo - Diagnostics, 2021 - mdpi.com
Chimerism analysis is a well-established method for monitoring the state of hematopoietic
stem cell transplantation (HSCT) over time by analyzing peripheral blood or bone marrow …

Current trends in applications of circulatory microchimerism detection in transplantation

H Andrikovics, Z Őrfi, N Meggyesi, A Bors… - International Journal of …, 2019 - mdpi.com
Primarily due to recent advances of detection techniques, microchimerism (the proportion of
minor variant population is below 1%) has recently gained increasing attention in the field of …

[HTML][HTML] Digital PCR to assess hematopoietic chimerism after allogeneic stem cell transplantation

T Stahl, MU Böhme, N Kröger, B Fehse - Experimental hematology, 2015 - Elsevier
Analysis of hematopoietic chimerism after allogeneic stem cell transplantation represents a
crucial method to evaluate donor-cell engraftment. Whereas sensitivity of classical …

Chimerism analysis in peripheral blood using indel quantitative real-time PCR is a useful tool to predict post-transplant relapse in acute leukemia

N Jacque, S Nguyen, JL Golmard, M Uzunov… - Bone marrow …, 2015 - nature.com
Detection of increasing mixed chimerism (IMC) using standard PCR correlates with relapse
after allo-SCT for acute leukemias (ALs). Quantitative real-time PCR of insertion/deletion …

Lineage-specific early complete donor chimerism and risk of relapse after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia

H Lindahl, S Vonlanthen, D Valentini… - Bone Marrow …, 2022 - nature.com
Recipient–donor chimerism is routinely analyzed after allogeneic hematopoietic stem cell
transplantation (HSCT) to monitor engraftment and graft rejection. For malignancies …

[HTML][HTML] Clinical utility of quantitative PCR for chimerism and engraftment monitoring after allogeneic stem cell transplantation for hematologic malignancies

M Ahci, K Stempelmann, U Buttkereit, P Crivello… - Biology of Blood and …, 2017 - Elsevier
Although quantitative PCR (qPCR) has been explored for chimerism monitoring after
allogeneic stem cell transplantation (SCT), evidence regarding its clinical utility compared …

Quantitative chimerism: an independent acute leukemia prognosis indicator following allogeneic hematopoietic SCT

XY Qin, GX Li, YZ Qin, Y Wang, FR Wang… - Bone Marrow …, 2014 - nature.com
This study evaluates the prognostic significance of quantitative chimerism to monitor minimal
residual disease and predict relapse in acute leukemia (AL) patients following allogeneic …

Digital PCR panel for sensitive hematopoietic chimerism quantification after allogeneic stem cell transplantation

T Stahl, C Rothe, MU Böhme, A Kohl, N Kröger… - International journal of …, 2016 - mdpi.com
Accurate and sensitive determination of hematopoietic chimerism is a crucial diagnostic
measure after allogeneic stem cell transplantation to monitor engraftment and potentially …

[HTML][HTML] Monitoring of hematopoietic chimerism after transplantation for pediatric myelodysplastic syndrome: real-time or conventional short tandem repeat PCR in …

AM Willasch, H Kreyenberg, N Shayegi… - Biology of blood and …, 2014 - Elsevier
Quantitative real-time PCR (qPCR) has been proposed as a highly sensitive method for
monitoring hematopoietic chimerism and may serve as a surrogate marker for the detection …

[HTML][HTML] Chimerism monitoring after allogeneic hematopoietic stem cell transplantation using quantitative real-time PCR of biallelic insertion/deletion polymorphisms

SY Kim, MH Jeong, N Park, E Ra, H Park… - The Journal of Molecular …, 2014 - Elsevier
An accurate and sensitive determination of chimerism status is mandatory after allogeneic
hematopoietic stem cell transplantation. We evaluated the performance of the AlleleSEQR …