Optical imaging probes for selective detection of butyrylcholinesterase

M Dirak, J Chan, S Kolemen - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Butyrylcholinesterase (BChE), a member of the human serine hydrolase family, is an
essential enzyme for cholinergic neurotransmission as it catalyzes the hydrolysis of …

A novel near-infrared fluorescent probe for high-sensitivity detection of butyrylcholinesterase in various pathological states

Y Jiang, H Cui, Q Yu - Spectrochimica Acta Part A: Molecular and …, 2024 - Elsevier
Butyrylcholinesterase (BChE) is a crucial hydrolytic enzyme predominantly synthesized in
the liver, playing a significant role in conditions like liver disorders, diabetes, Alzheimer's …

A novel turn-on near-infrared fluorescent probe for highly sensitive in vitro and in vivo detection of acetylcholinesterase activity

L Xing, P Ma, F Chen - Spectrochimica Acta Part A: Molecular and …, 2024 - Elsevier
Acetylcholinesterase (AChE) is a key enzyme in the cholinergic pathway of the nervous
systems, with its aberrant expression linked to various diseases. In this study, we have …

Benzorhodol derived far-red/near-infrared fluorescent probes for selective and sensitive detection of butyrylcholinesterase activity in living cells and the non-alcoholic …

Z Guo, J Peng, Z Zhou, F Wang, M He, S Lu… - Analytical …, 2024 - pubs.rsc.org
Liver diseases are a growing public health concern and the development of non-alcoholic
fatty liver disease (NAFLD) has a significant impact on human metabolism …

Near-Infrared Fluorescent Probe for Ultrasensitive Detection of Organophosphorus Pesticides and Visualization of Their Interaction with Butyrylcholinesterase in …

Z Zhang, J Li, B Yang, M Ma, X Ding, H Shi, P Ma… - Talanta, 2024 - Elsevier
The toxicity of organophosphorus pesticides (OPs) can catastrophically cause liver cell
damage and inhibit the catalytic activity of cholinesterase. We designed and synthesized a …

Enzyme-activated binary assembly for targeted, controlled delivery of anti-liver cancer compounds

D Wang, X Chen, S Chen, H Wang, J Yang, J He… - Carbohydrate …, 2024 - Elsevier
Liver cancer is the third leading cause of cancer deaths globally. The use of
Hydroxycamptothecin (HCPT) as a first-line chemotherapeutic agent for liver, lung, and …

Enzyme-Triggered Supramolecular Nanocarriers for the Load, Deliver, and Controlled Release of Anti-Tumor Drugs

D Wang, X Chen, S Chen, H Wang, JM Yang… - Deliver, and Controlled … - papers.ssrn.com
Liver cancer is the third leading cause of cancer deaths globally. The use of
Hydroxycamptothecin (HCPT) as a first-line chemotherapeutic agent for liver, lung, and …